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Table 3 Rates of severe adverse perinatal outcome, sensitivity, specificity, positive and negative likelihood ratios per centile group of the Visser, INTERGROWTH, and Hoftiezer birth weight standard

From: Associations of severe adverse perinatal outcomes among continuous birth weight percentiles on different birth weight charts: a secondary analysis of a cluster randomized trial

Centile group

Visser

 

INTER-

GROWTH

Hoftiezer

 

N

SAPOa, n (%)

N

SAPOa, n (%)

N

SAPOa, n (%)

 < p3

211

13 (6.2)

108

13 (12.0)

349

30 (8.6)

p3 to < p5

191

9 (4.7)

93

5 (5.4)

250

11 (4.4)

p5 to < p10

599

17 (2.8)

267

13 (4.9)

579

16 (2.8)

p10 to < p25

1823

30 (1.6)

1002

28 (2.8)

1886

33 (1.7)

p25 to < p75

6637

101 (1.5)

5877

88 (1.5)

6477

82 (1.3)

p75 to < p90

1973

24 (1.2)

2821

35 (1.2)

2014

25 (1.2)

p90 to < p95

681

7 (1.0)

1243

13 (1.0)

677

7 (1.0)

p95 to p97

403

5 (1.2)

545

5 (0.9)

272

3 (1.1)

 > p97

435

9 (2.1)

993

15 (1.5)

393

8 (2.0)

Sensitivity, % (95%CI) a

  < p3

6.0 (3.3; 10.1)

6.1 (3.3; 10.1)

14.0 (9.6; 19.3)

  < p5

10.2 (6.5; 15.1)

8.4 (5.0; 12.9)

19.1 (14.1; 25.0)

  < p10

18.1 (13.2; 24.0)

14.4 (10.0; 19.8)

26.5 (20.7; 32.9)

  < p25

32.1 (25.9; 38.8)

27.4 (21.6; 33.9)

41.9 (35.2; 48.8)

  > p75

20.9 (15.7; 27.0)

31.6 (25.5; 38.3)

20.0 (14.9; 26.0)

  > p90

9.8 (6.2; 14.5)

15.3 (10.8; 20.9)

8.4 (5.0; 12.9)

  > p95

6.5 (3.6; 10.7)

9.3 (5.8; 14.0)

5.1 (2.6; 9.0)

  > p97

4.2 (1.9; 7.8)

7.0 (4.0; 11.3)

3.7 (1.6; 7,2)

Specificity, % (95% CI)a

  < p3

98.4 (98.2; 98.7)

99.3 (99.1; 99.4)

97.5 (97.2; 97.8)

  < p5

97.0 (96.7; 97.3)

98.6 (98.3; 98.8)

95.6 (95.2; 96.0)

  < p10

92.5 (92.0; 92.9)

96.6 (96.2; 96.9)

91.2 (90.7; 91.7)

  < p25

78.4 (77.7; 79.1)

88.9 (88.4; 89.5)

76.6 (75.8; 77.3)

  > p75

72.9 (72.2; 73.7)

56.6 (55.7; 57.4)

73.9 (73.1; 74.6)

  > p90

88.2 (87.7; 88.8)

78.4 (77.7; 79.1)

89.6 (89.0; 90.1)

  > p95

93.5 (93.1; 94.0)

88.1 (87.5; 88.7)

94.8 (94.4; 95.2)

  > p97

96.7 (96.3; 97.0)

92.3 (91.8; 92.8)

97.0 (96.7; 97.3)

Positive likelihood ratio (95%CI)a

  < p3

3.89 (2.26; 6.71)

8.10 (4.61; 14.24)

5.55 (3.91; 7.87)

  < p5

3.43 (2.28; 5.16)

5.83 (3.66; 9.27)

4.33 (3.25; 5.78)

  < p10

2.40 (1.80; 3.21)

4.20 (3.00; 5.89)

3.00 (2.38; 3.77)

  < p25

1.48 (1.22; 1.81)

2.48 (1.98; 3.09)

1.79 (1.52; 2.10)

  > p75

0.77 (0.60; 1.00)

0.73 (0.60; 0.89)

0.77 (0.59; 1.00)

  > p90

0.83 (0.55; 1.25)

0.71 (0.52; 0.98)

0.80 (0.51; 1.25)

  > p95

1.01 (0.60; 1.68)

0.78 (0.51; 1.19)

0.99 (0.56; 1.77)

  > p97

1.25 (0.66; 2.39)

0.91 (0.56; 1.49)

1.23 (0.62; 2.44)

Negative likelihood ratio (95% CI)a

  < p3

0.95 (0.92; 0.99)

0.95 (0.92; 0.98)

0.88 (0.84; 0.93)

  < p5

0.93 (0.88; 0.97)

0.93 (0.89; 0.97)

0.85 (0.79; 0.90)

  < p10

0.89 (0.83; 0.94)

0.89 (0.84; 0.94)

0.81 (0.74; 0.87)

  < p25

0.87 (0.79; 0.95)

0.82 (0.75; 0.89)

0.76 (0.68; 0.85)

  > p75

1.08 (1.01; 1.16)

1.21 (1.10; 1.33)

1.08 (1.01; 1.16)

  > p90

1.02 (0.98; 1.07)

1.08 (1.02; 1.14)

1.02 (0.98; 1.07)

  > p95

1.00 (0.96; 1.04)

1.03 (0.99; 1.07)

1.00 (0.97; 1.03)

  > p97

0.99 (0.96; 1.02)

1.01 (0.97; 1.05)

0.99 (0.97; 1.02)

  1. Numbers indicate absolute numbers (n) and percentages (%)
  2. aSevere adverse perinatal outcomes