Table 1 Baseline data and controlled ovarian hyperstimulation response characteristics in 493 DOR women with and without endometrioma
From: Does current ovarian endometrioma increase the time for DOR patients to reach live birth in IVF?
All (n = 493) | LB (n = 163) | |||||
|---|---|---|---|---|---|---|
Group A Endometrioma | Group B Non- Endometrioma | P | Group A1 Endometrioma | Group B1 Non- Endometrioma | P | |
Number of patients | 90 | 403 | 31 | 132 | ||
OPU cycles | 191 | 888 | 55 | 238 | ||
ET cycles | 114 | 503 | 45 | 178 | ||
Age (years) | 36.1 ± 5.1 | 37.7 ± 5.3 | 0.72 | 32.6 ± 4.2 | 34.7 ± 4.3 | 0.40 |
AFC | 4.3 ± 2.3 | 4.5 ± 2.1 | 0.18 | 5.3 ± 2.2 | 5.0 ± 2.0 | 0.49 |
AMH (ng/ml) | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.13 | 0.6 ± 0.3 | 0.7 ± 0.3 | 0.02 |
bFSH (mIU/mL) | 9.4 ± 5.9 | 8.8 ± 5.4 | 0.47 | 10.0 ± 6.2 | 8.2 ± 5.5 | 0.24 |
bLH (mIU/mL) | 3.4 ± 1.9 | 3.5 ± 2.2 | 0.95 | 3.5 ± 1.6 | 3.1 ± 1.8 | 0.88 |
bE2 (pmol/L) | 155.0 ± 87.1 | 164.9 ± 151.6 | 0.22 | 147.8 ± 88.7 | 161.1 ± 158.2 | 0.72 |
BMI (km/m2) | 21.2 ± 2.8 | 22.3 ± 2.8 | 0.86 | 20.9 ± 3.1 | 21.5 ± 2.8 | 0.60 |
Duration of infertility (years) | 3.9 ± 3.0 | 3.8 ± 3.7 | 0.21 | 3.3 ± 2.6 | 3.2 ± 3.0 | 0.51 |
Primary fertility | 35/90 (38.9%) | 111/403 (27.5%) | 0.03 | 17/31 (54.8%) | 54/131 (41.2%) | 0.17 |
Secondary fertility | 55/90 (61.1%) | 292/403 (72.5%) | 0.03 | 14/31 (45.2%) | 77/131 (58.8%) | 0.17 |
range of diameters of endometriomas (cm) | 3.0–5.5 | – | 3.0–4.8 | – | ||
average size of endometriomas (cm) | 4.0 ± 0.6 | – | 3.6 ± 0.4 | – | ||
GnRH-agonist protocol n (%) | 26 (13.6) | 103 (11.6) | 0.44 | 13 (23.6) | 49 (20.6) | 0.62 |
GnRH-antagonist protocol n (%) | 162 (84.8) | 777 (87.5) | 0.32 | 42 (76.4) | 189 (79.4) | 0.62 |
Natural/modified natural n (%) | 3 (1.6) | 8 (0.9) | 0.66 | 0 | 0 | |
Starting dose of gonadotropins (IU) | 195.6 ± 70.3 | 206.8 ± 66.2 | 0.15 | 208.4 ± 71.0 | 223.7 ± 61.6 | 0.11 |
Duration of stimulation (days) | 8.1 ± 3.4 | 8.4 ± 3.5 | 0.89 | 9.4 ± 3.2 | 9.0 ± 3.2 | 0.78 |
Total doses of gonadotropins (IU) | 1730.4 ± 1064.4 | 1835.7 ± 1040.2 | 0.66 | 2168.6 ± 1145.4 | 2071.8 ± 1015.4 | 0.18 |
Serum LH at the day of HCG (mIU/mL) | 5.8 ± 6.2 | 5.4 ± 6.7 | 0.93 | 3.7 ± 4.1 | 3.5 ± 3.4 | 0.93 |
Serum E2 at the day of HCG (pg/mL) | 3896.5 ± 2631.6 | 3792.9 ± 2859.0 | 0.70 | 4601.2 ± 2671.8 | 4561.3 ± 3032.7 | 0.67 |
Serum P at the day of HCG (ng/mL) | 1.7 ± 1.1 | 1.6 ± 1.1 | 0.5 | 1.7 ± 0.9 | 1.7 ± 1.1 | 0.07 |
Endometrial thickness at the day of HCG (mm) | 9.3 ± 2.2 | 8.9 ± 3.0 | 0.13 | 10.1 ± 2.7 | 9.6 ± 2.5 | 0.65 |