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Table 4 Hemoglobin level, by malaria infection and aspirin exposure

From: The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries

Hemoglobin cut-point Overall Malaria Negative Malaria positive
N (w/ and w/o outcome) PR (95% CI) N (w/ and w/o outcome) PR (95% CI) N (w/ and w/o outcome) PR (95% CI)
Hemoglobin ≤ 8 g/dL
 Aspirin 11/618 0·91 (0·04, 2·04) 3/376 0·58 (0·14, 2·43) 8/242 1·16 (0·43, 3·14)
 Placebo 12/610   5/364   7/246  
Hemoglobin ≤ 9 g/dL
 Aspirin 43/586 1·06 (0·70, 1·58) 10/369 0·57 (0·27, 1·23) 33/217 1·34 (0·82, 2·18)
 Placebo 42/580   17/352   25/228  
Hemoglobin ≤ 10 g/dL
 Aspirin 122/507 1·01 (0·80, 1·26) 49/330 1·04 (0·71, 1·51) 73/177 1·00 (0·76, 1·31)
 Placebo 120/502   46/323   74/179  
Hemoglobin ≤ 11 g/dL
 Aspirin 266/363 1·03 (0·90, 1·17) 128/251 1·07 (0·87, 1·31) 138/112 1·00 (0·86, 1·18)
 Placebo 256/366   117/252   139/114  
  1. Note: Hemoglobin measured between 26–30 weeks. Malaria in early pregnancy measured between 6–13 6/7 weeks gestation