Table 4 Diagnostic value of DWI parameters in differentiating PAS disorders
group | AUC(95%CI) | Optimal cutoff value | Youden index | sensitivity | specificity | +LR | -LR |
|---|---|---|---|---|---|---|---|
WP-normal vs WP-PAS | |||||||
 f mean(%) | 0.67 (0.56, 0.79) | 44 | 0.36 | 50.77% | 85.19% | 3.43 | 0.58 |
 D mean(∙10−3 mm2/s) | 0.69 (0.58, 0.80) | 1.61 | 0.31 | 75.38% | 55.56% | 1.70 | 0.44 |
 D max(∙10−3 mm2/s) | 0.64 (0.52, 0.76) | 1.75 | 0.29 | 95.38% | 33.33% | 1.43 | 0.14 |
 D* mean(∙10−3 mm2/s) | 0.68 (0.57, 0.79) | 27.29 | 0.34 | 96.92% | 37.04% | 1.54 | 0.08 |
 MD mean(×10−3 mm2/s) | 0.68 (0.57,0.79) | 3.11 | 0.37 | 55.38% | 81.48% | 2.99 | 0.55 |
 MD min(×10−3 mm2/s) | 0.63 (0.51, 0.75) | 0.50 | 0.24 | 83.08% | 40.74% | 1.40 | 0.42 |
 MD max(×10−3 mm2/s) | 0.71 (0.60, 0.82) | 7.22 | 0.49 | 63.08% | 77.78% | 2.84 | 0.48 |
 Mkmean | 0.63 (0.51, 0.75) | 0.64 | 0.28 | 53.85% | 74.07% | 2.08 | 0.62 |
 Combined (D mean and D max) | 0.78 (0.68, 0.87) | 0.46 | 0.48 | 81.54% | 66.67% | 2.45 | 0.28 |
AP vs WP-normal | |||||||
 ADC max(∙10−3 mm2/s) | 0.83 (0.75, 0.91) | 2.55 | 0.57 | 83.08% | 74.07% | 3.20 | 0.23 |
 f mean(%) | 0.62 (0.50 0.74) | 44 | 0.34 | 49.23% | 85.19% | 3.32 | 0.60 |
 D mean(∙10−3 mm2/s) | 0.73 (0.63, 0.84) | 1.67 | 0.38 | 52.31% | 85.19% | 3.53 | 0.56 |
 D max(∙10−3 mm2/s) | 0.85 (0.77, 0.93) | 2.41 | 0.60 | 86.15% | 74.07% | 3.32 | 0.19 |
 D* mean(∙10−3 mm2/s) | 0.75 (0.65, 0.85) | 30.38 | 0.41 | 89.23% | 51.85% | 1.85 | 0.21 |
 MD mean(×10−3 mm2/s) | 0.68 (0.57, 0.79) | 3.12 | 0.37 | 55.38% | 81.485 | 2.99 | 0.55 |
 Mkmean | 0.63 (0.51, 0.75) | 0.64 | 0.26 | 52.31% | 74.07% | 2.02 | 0.64 |
 Mkmax | 0.64 (0.52, 0.76) | 1.52 | 0.30 | 75.38% | 55.56% | 1.70 | 0.44 |
 Combined (D mean and D max) | 0.93 (0.89, 0.98) | 0.46 | 0.72 | 83.08% | 88.89% | 7.48 | 0.19 |