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Table 2 Trimester-specific reference intervals for TSH (mIU/L)

From: Accurate interpretation of thyroid dysfunction during pregnancy: should we continue to use published guidelines instead of population-based gestation-specific reference intervals for the thyroid-stimulating hormone (TSH)?

Trimester

N*

Median

Min-max

Lower limit

Upper limit

Lower 90% CI

Upper 90% CI

P value*

T1

670

1.25

0.03-4.47

0.23

3.09

0.19-0.27

2.93-3.24

 

T2

666

1.54

1.17-4.07

0.54

3.01

0.49-0.59

2.89-3.12

0.000*

T3

369

1.62

0.31-4.52

0.66

3.23

0.61-0.73

3.05-3.42

0.058

  1. * P value was calculated for median TSH values comparing with the upper trimester
  2. As a result of excluding the outliers by the Tukey test in each trimester, the net sample size was slightly different from the one indicated in Table 1
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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