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Table 2 Threshold effect analysis of E2 level (100pg/mL) on the clinical pregnancy rate

From: The relationship between serum oestrogen levels and clinical outcomes of hormone replacement therapy-frozen embryo transfer: a retrospective clinical study

Outcome

Clinical pregnancy

Model I (linear)

OR

95% CI

p value

Linear effect

0.986

(0.980, 0.992)

< 0.001

Model II (polyline)

OR

95% CI

p value

Predicted threshold (K, E 2 level, 100pg/mL)

14

Effect 1 (< K)

0.975

(0.960, 0.989)

< 0.001

Effect 2 (> K)

0.999

(0.983, 1.015)

0.907

variability of effectiveness

0.172

(0.019, 0.324)

 

Logarithmic likelihood ratio test

0.042

  1. When the E2 level was less than 1400 pg/mL, there was a negative relationship between E2 levels and the clinical pregnancy rate
  2. E2 oestrogen, OR odds ratio, CI confidence interval, K predicted threshold