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Table 2 Comparison of clinical data between the adverse outcomes and non-adverse outcomes groups in the training set (N = 729)

From: Establishment of a nomogram model for predicting adverse outcomes in advanced-age pregnant women with preterm preeclampsia

Variables

No adverse outcomes n = 619

adverse outcomes n = 110

P

Age, years

38.36 ± 2.64

38.33 ± 2.89

0.940

Number of pregnancies

3 [2,4]

3 [2,4]

0.435

Number of births

1 [1,1]

1 [1,1]

0.454

Systolic blood pressure, mmHg

158.43 ± 23.52

162.92 ± 23.17

0.065

Diastolic blood pressure, mmHg

98.44 ± 15.98

102.08 ± 15.39

0.027

Body mass index (BMI), kg/m2

30.27 ± 3.02

30.09 ± 2.50

0.521

Family history of cardiovascular disease

172 (27.8%)

31 (28.2%)

0.932

Past history

 Hypertension

125 (20.2%)

21 (19.1%)

0.790

 Eclampsia or PE

22 (3.6%)

4 (3.6%)

0.966

 Irregular menstruation before pregnancy

70 (11.3%)

15 (13.6%)

0.483

Symptoms

 Headache

117 (18.9%)

21 (19.1%)

0.963

 Dizzy

106 (17.1%)

21 (19.1%)

0.616

 Oedema of the lower limbs

87 (14.1%)

16 (14.5)

0.892

 Blurred vision

58 (9.4%)

13 (11.8%)

0.425

Neutrophil count (NC), 109/L

9.05 ± 4.16

9.05 ± 4.16

0.010

Monocyte count (MC), 109/L

0.59 ± 0.23

0.62 ± 0.44

0.372

Lymphocyte count (LC), 109/L

1.81 ± 0.58

1.71 ± 0.60

0.102

White blood cell count (WBC), 109/L

10.22 ± 3.06

11.46 ± 4.43

0.013

Red blood cell count (RBC), 1012/L

4.12 ± 0.47

4.06 ± 0.57

0.270

Haemoglobin (HGB), g/L

121.03 ± 15.55

120.67 ± 17.08

0.824

Platelet count (PLT), 109/L

203.11 ± 62.52

171.98 ± 64.41

< 0.001

D-dimer, mg/L

4.32 ± 1.21

4.21 ± 1.32

0.821

Prothrombin time (PT), seconds

9.60 [8.90,10.11]

10.07 [9.17,10.50]

< 0.001

Prothrombin time activity (PTA), %

142.00 [133.89,158.00]

137.29 [129.17,151.00]

0.009

Thrombin time (TT), Seconds

14.76 [13.40,15.66]

15.81 [13.80,16.50]

< 0.001

Alanine aminotransferase (ALT), U/L

23.06 ± 14.22

25.69 ± 10.50

< 0.001

Aspartate aminotransferase (AST), U/L

24.49 ± 13.09

30.52 ± 12.93

< 0.001

Uric acid (UA), μmol/L

372.72 ± 81.15

412.19 ± 70.47

< 0.001

Triglyceride (TG), mmol/L

3.34 ± 1.26

3.29 ± 1.09

0.671

Total cholesterol (TCHO), mmol/L

6.11 ± 1.46

6.11 ± 1.41

0.749

Low-density lipoprotein (LDL), mmol/L

3.16 ± 0.83

3.20 ± 0.82

0.645

High-density lipoprotein (HDL), mmol/L

1.97 ± 0.39

1.94 ± 0.44

0.499

Lactate dehydrogenase (LDH), U/L

234.54 ± 68.21

290.87 ± 77.37

< 0.001

Blood urea nitrogen (BUN), mmol/L

4.66 ± 1.26

5.51 ± 1.46

< 0.001

Biparietal diameter (BPD), cm

7.78 ± 1.16

7.83 ± 0.94

0.772

Head circumference (HC), cm

28.62 ± 2.97

28.64 ± 2.40

0.632

Femur length (FL), cm

5.68 ± 1.04

5.73 ± 0.90

0.726

Amniotic fluid index (AFI), cm

11.65 ± 2.81

12.04 ± 2.86

0.081

Foetal heart rate (FHR), beats/minute

143.69 ± 8.18

143.75 ± 8.83

0.940

Umbilical artery blood velocity (S/D)

2.76 ± 0.46

2.84 ± 0.37

< 0.001

Pulsatility index (PI)

1.04 ± 0.21

1.10 ± 0.21

0.004

Resistance index (RI)

0.62 ± 0.06

0.63 ± 0.05

0.004