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Table 1 Baseline characteristics of mothers by HIV status at 1st ANC visit and STI prevalence during pregnancy in South Africa (2016–2019)

From: Impact of aetiological screening of sexually transmitted infections during pregnancy on pregnancy outcomes in South Africa

 

All (n, %)

Women living without HIV

Women living with HIV

 

Total

619

133 (21)

486 (79)

p-value

Sociodemographic characteristics

 Maternal age (median, IQR) years

30 (25–34)

26 (23–32)

30 (26–34)

< 0.001

 GA at booking (median, IQR) weeks

18 (13–24)

19 (13–24)

18 (13–23)

0.78

 Gravidity (median, IQR)

3 (2–4)

2 (1–3)

3 (2–4)

< 0.001

 Parity (median, IQR)

1 (1–2)

1 (0–2)

2 (1–2)

< 0.001

Education level completed

 Primary

220 (36)

3 (2)

217 (45)

< 0.001

 Secondary

368 (59)

121 (91)

247 (51)

 

 Tertiary (College/University)

31 (5)

9 (7)

22 (4)

 

Relationship with father of child

 Married/Cohabiting

305 (49)

65 (49)

240 (49)

0.91

 Not married/ Non-cohabiting

289 (47)

66 (49)

223 (46)

 

 No relationship

25 (4)

2 (2)

23 (5)

 

Employment status

 Formal employment

211 (34)

36 (27)

175 (36)

0.06

 Informal employment

18 (3)

2 (2)

16 (3)

 

 Unemployed/attending school

390 (63)

95 (71)

295 (61)

 

Site

 Tshwane District

380 (61)

0 (0)

380 (78)

–

 Cape Town

239 (39)

133 (100)

106 (22)

 

Clinical characteristic in this pregnancy

 Any STI during pregnancy or postpartum

  Yes

249 (40)

40 (30)

209 (43)

0.007

  No

370 (60)

93 (70)

277 (57)

 

 Any STI at 1st ANC visit

  Yes

228 (37)

36 (27)

192 (40)

0.008

  No

391 (63)

97 (72)

294 (60)

 

 Any STI at 1st postnatal visit (na = 571)

  Yes

45 (8)

4 (3)

45 (9)

0.03

  No

526 (92)

120 (97)

441 (91)

 

 Any STI at 1st ANC and 1st postnatal visit

  Yes

30 (5)

1 (1)

29 (6)

0.01

  No

589 (95)

132 (99)

457 (94)

 

 Chlamydia trachomatis at 1st ANC

  Yes

158 (26)

27 (20)

131 (27)

0.11

  No

461 (74)

106 (80)

355 (73)

 

 Neisseria gonorrhoea at 1st ANC

  Yes

35 (6)

3 (2)

32 (7)

0.05

  No

584 (94)

130 (98)

454 (93)

 

 Trichomonas vaginalis

  Yes

114 (18)

14 (11)

100 (21)

0.008

  No

505 (82)

119 (89)

386 (79)

 

 bCoinfections of CT, NG or TV at 1st ANC

  Yes

72 (12)

8 (6)

64 (13)

0.02

  No

547 (88)

125 (82)

422 (87)

 

Sexual behaviour during pregnancy

 Vaginal sex

551 (89)

126 (94)

425 (87)

0.01

 Oral sex

36 (6)

6 (5)

30 (6)

0.46

 Anal sex

14 (2)

3 (2)

11 (2)

0.99

 2+ sex partners in the past 3 months

18 (3)

1 (1)

17 (4)

0.09

Suspect partner of having another sex partner

 No

284 (46)

77 (58)

201 (43)

0.02

 Yes

212 (34)

35 (36)

177 (38)

 

 Don’t know

117 (19)

20 (15)

97 (20)

 

 N/Ac

6 (1)

1 (1)

5 (1)

 

Partner’s serostatus

 Concordant HIV status

216 (35)

92 (69)

124 (26)

< 0.001

 Serodiscordant

92 (15)

4 (3)

88 (18)

 

 Serostatus unknown

311 (50)

37 (28)

274 (56)

 
  1. IQR Interquartile range, n number of participants, GA gestational age, ANC antenatal care
  2. anumber of women at 1st postnatal visit excluding pregnancy losses
  3. bCo-infection with at least two infections of Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis
  4. cRefers to women who didn’t have a partner, they were not in a relationship