Table 1 Baseline Characteristics and Outcomes of Vaccinated vs. Unvaccinated Patients
From: Safety of SARS-CoV-2 vaccination during pregnancy- obstetric outcomes from a large cohort study
Vaccinated n = 2305 | Unvaccinated n = 3313 | p | |
|---|---|---|---|
Maternal age | 30 (26, 34) | 30 (26, 34) | 0.009 |
Body mass index (kg/m2) | 26.4 (23.4, 30.1) | 25.6 (22.2, 29.4) | < 0.001 |
Parity | 1 (0,3) | 2 (0,3) | 0.27 |
Nulliparous | 611 (26.5) | 838 (25.3) | 0.31 |
Smoking | 79 (3.4) | 88 (2.7) | 0.09 |
Primary Outcomes | |||
Preterm birth | 127 (5.5) | 204 (6.2) | 0.31 |
Small for gestational age | 142 (6.2) | 233 (7.0) | 0.20 |
Secondary outcomes | |||
Gestational age at delivery, weeks | 39.7 (38.5, 40.4) | 39.7 (38.7, 40.4) | 0.33 |
Cesarean delivery | 358 (15.5) | 529 (16.0) | 0.66 |
Postpartum hemorrhage (> 500 mL) | 79 (3.4) | 104 (3.1) | 0.55 |
Intrauterine fetal demise | 20 (0.87) | 33 (1.0) | 0.62 |
Birthweight, g | 3280 (2980, 3590) | 3260 (2955, 3575) | 0.083 |
Apgar 5 min | 10 (10,10) | 10 (10,10) | 0.63 |
5 min Apgar < 7 | 42 (1.8) | 63 (1.9) | 0.83 |
Umbilical arterial pH | 7.28 (7.21, 7.34) | 7.28 (7.22, 7.34) | 0.32 |
Umbilical pH < 7.1 | 89 (7.4) | 122 (6.8) | 0.57 |
Umbilical arterial base excess | -4.1 (-6.0, -2.7) | -3.9 (-5.7, -2.5) | 0.007 |
Hypertensive disorder of pregnancy | 25 (1.1) | 44 (1.3) | 0.42 |
Gestational diabetes | 222 (9.6) | 275 (8.3) | 0.08 |