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Table 3 Bivariable and multivariable logistic regression analysis of factors associated with failed induction of labor among women undergoing induction at University of Gondar Specialized Hospital, Northwest Ethiopia, 2020

From: Failed induction of labor and associated factors among women undergoing induction at University of Gondar Specialized Hospital, Northwest Ethiopia

Variables

Failed induction of labor

95% Confidence Interval

Name and Label

Yes

No

COR

AOR

Age in years

  ≤ 30

105(19.3%)

439(80.7%)

1

1

  > 30

69(40.8%)

100(59.2%)

2.9(2.0,4.2)***

3.7(2.2,6.2)***

Residence

 Urban

65(14.2%)

392(85.8%)

1

1

 Rural

108(42.7%)

145(57.3%)

4.5(3.1,6.5)***

3.7(2.4,5.8)***

Parity status at time of induction

 Nulliparous

139(26.7%)

381(73.3%)

1.6(1.1,2.5)*

2.1(1.2,3.7)**

 Multiparous

35(18.1%)

158(81.9%)

1

1

Birth weight in the current pregnancy

  < 2500

54(34.4%)

103(65.6%)

2.0(1.4,2.9)***

1.5(0.9,2.5)

 2500–3999

103(20.6%)

396(79.4%)

1

1

  ≥ 4000

15(35.7%)

27(64.3%)

2.1(1.1,4.2)*

1.7(0.7,4.2)

Gestational age at the time of induction

  ≤ 37

69(27.4%)

183(72.6%)

1

 

 38–40

55(20.9%)

208(79.1%)

0.7(0.5,1.1)

 

  ≥ 41

28(18.9%)

120(81.1%)

0.6(0.4,1.0)

 

Pre-induction bishop score

  ≤ 5

120(37.4%)

201(62.6%)

4.3(2.9,6.3)***

3.4(2.2,5.4)***

  > 5

45(12.2%)

325(87.8%)

1

1

Duration of the latent phase

  ≤ 18 h

155(24.1%)

489(75.9%)

1

 

  > 18 h

10(29.4%)

24(70.6%)

1.3(0.6,2.8)

 

Post-term pregnancy

 No

149(27.2%)

398(72.8%)

1

1

 Yes

15(15.6%)

81(84.4%)

0.5(0.3,0.9)*

1.4(0.7,3.0)

Premature rupture of membrane

 No

93(22.4%)

322(77.6%)

1

1

 Yes

71(31.1%)

157(68.9%)

1.6(1.1,2.3)*

2.7(1.5,4.6)***

Intra-uterine growth restriction

 No

153(25.7%)

442(74.3%)

1

 

 Yes

11(22.9%)

37(77.1%)

0.9(0.4,1.7)

 

Pregnancy-induced hypertension

 No

90(20%)

359(80%)

1

1

 Yes

74(38.1%)

120(61.9%)

2.5(1.7,3.6)***

4.0(2.3,7.1)***

Diabetic Mellitus

 No

152(24.9%)

458(75.1%)

1

 

 Yes

12(36.4%)

21(63.6%)

1.7(0.8,3.6)

 

Antepartum hemorrhage

 No

132(25.6%)

384(74.4)

1

 

 Yes

32(25.2%)

95(74.8%)

1.0(0.6,1.5)

 

Oligohydramnios

 No

136(25.4%)

400(74.6%)

1

 

 Yes

28(26.2%)

79(73.8%)

1.0(0.7,1.7)

 

Polyhydramnios

 No

153(25.1%)

456(74.9%)

1

 

 Yes

11(32.4%)

23(67.6%)

1.4(0.7,2.9)

 

Method of induction

 Oxytocin infusion only

138(26%)

393(74%)

1

1

 Misoprostol only

11(30.6%)

25(69.4%)

1.3(0.6,2.6)

 

 ARM with oxytocin

14(15.2%)

78(84.8%)

0.5(0.3,0.9)*

0.2(0.1,0.4)***

 Balloon catheter with oxytocin

11(20.4%)

43(79.6%)

0.7(0.4,1.5)

 

Maximum oxytocin dose used

  ≤ 5 IU

93(26.9%)

253(73.1%)

1

 

 6-10 IU

33(20.9%)

125(79.1%)

0.7(0.5,1.1)

 

  > 10 IU

12(44.4%)

15(55.6%)

2.2(0.9,4.8)

 
  1. AOR: Adjusted Odds Ratio, COR Crude Odds Ratio, 1: Reference category
  2. *Significant at p < 0.25 but > 0.01
  3. **Significant at P = 0.01
  4. ***Significant at P = 0.000