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Table 2 Logistic regression for pre-existing multimorbidity by women’s characteristics

From: Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a population-based cross-sectional study

Characteristics CPRD (England), n = 13,075 SAIL (Wales), n = 27,782 SMR (Scotland), n = 6099
Unadjusted OR
(95% CI)
Adjusted OR
(95% CI)
Unadjusted OR
(95% CI)
Adjusted OR
(95% CI)
Unadjusted OR
(95% CI)
Adjusted OR
(95% CI)
Age categories (5 yearly)
 15–19 Ref Ref Ref Ref Ref Ref
 20–24 1.60 (1.34 −1.90) 1.17 (0.97 − 1.42) 1.64 (1.45 − 1.85) 1.10 (0.96 −1.26) 1.48 (1.11 −1.94) 1.42 (1.05 − 1.92)
 25–29 1.80 (1.52 −2.12) 1.21 (1.01 − 1.45) 1.93 (1.72 −2.17) 1.21 (1.06 −1.39) 1.36 (1.02 −1.81) 1.45 (1.07 − 1.95)
 30–34 1.84 (1.56 −2.17) 1.26 (1.05 − 1.52) 2.19 (1.94 −2.46) 1.36 (1.19 −1.56) 1.18 (0.89 −1.58) 1.32 (0.97 −1.80)
 35–39 1.95 (1.64 −2.32) 1.28 (1.06 −1.56) 2.54 (2.24 − 2.89) 1.64 (1.42 −1.90) 1.23 (0.90 −1.69) 1.37 (0.97 −1.93)
 40–44 2.55 (2.04 −3.20) 1.61 (1.26 −2.06) 3.19 (2.63 −3.88) 2.20 (1.77 −2.73) 1.04 (0.62 −1.75) 1.18 (0.68 −2.04)
 45–49 2.98 (1.74 −5.11) 1.81 (1.04 −3.17) 3.88 (1.94 −7.76) 4.11 (1.83 −9.26) 1.56 (0.42 −5.87) 1.67 (0.45 −6.93)
Gravidity
 1 Ref Ref Ref Ref Ref Ref
 2 1.07 (0.97 −1.18) 0.98 (0.89 −1.08) 1.20 (1.14 −1.26) 1.03 (0.97 −1.09) 1.09 (0.92 −1.30) 1.03 (0.86 −1.23)
 3 1.35 (1.22 −1.50) 1.18 (1.06 −1.32) 1.51 (1.40 −1.63) 1.16 (1.07 −1.27) 1.30 (1.07 −1.58) 1.17 (0.95 −1.43)
 4 1.52 (1.35 −1.72) 1.30 (1.15 −1.48) 1.89 (1.67 −2.15) 1.39 (1.21 −1.60) 1.77 (1.41 −2.21) 1.49 (1.17 −2.01)
  ≥ 5 2.11 (1.9 −2.35) 1.68 (1.50 −1.89) 2.73 (2.27 −3.29) 1.81 (1.48 −2.22) 2.70 (2.21 −3.34) 2.19 (1.75 −2.76)
 Missing 1.75 (0.18 −16.88) 1.31 (0.13 −13.43)
Ethnicity
 Asian /South Asiana 0.60 (0.52 −0.69) 0.66 (0.56 −0.77) 0.48 (0.39 −0.59) 0.53 (0.43 −0.66) 0.44 (0.26 −0.75) 0.51 (0.29 −0.87)
 Black 0.76 (0.63 −0.91) 0.73 (0.61 − 0.89) 0.31 (0.22 − 0.43) 0.31 (0.22 −0.45) 0.78 (0.27 −2.31) 0.86 (0.29 −2.58)
 Mixed 0.88 (0.67 −1.16) 0.95 (0.72 −1.26) 0.78 (0.54 −1.11) 0.86 (0.59 −1.27)
 Other 0.55 (0.44 − 0.70) 0.61 (0.48 − 0.77) 0.31 (0.23 − 0.42) 0.33 (0.24 − 0.45) 0.66 (0.38 −1.15) 0.59 (0.33 −1.05)
 White Ref Ref Ref Ref Ref Ref
 Missing 0.85 (0.78 −0.93) 0.94 (0.86 −1.03) 0.61 (0.58 −0.65) 0.74 (0.70 −0.78) 0.62 (0.51 −0.75) 0.63 (0.52 −0.77)
BMI (kg/m2)
 Underweight (< 18.5) 0.89 (0.73 −1.07) 0.91 (0.75 −1.10) 1.06 (0.94 −1.19) 1.08 (0.96 −1.22) 1.59 (0.96 −2.63) 1.27 (0.68 −1.93)
 Normal Weight (18.5–24.9) Ref Ref Ref Ref Ref Ref
 Overweight (25–29.9) 1.20 (1.10 −1.31) 1.16 (1.05 −1.27) 1.19 (1.11 −1.27) 1.17 (1.09 −1.25) 1.31 (1.06 −1.62) 1.33 (0.75 −2.16)
 Obese (30+) 1.69 (1.53 −1.86) 1.59 (1.44 −1.76) 1.57 (1.47 −1.69) 1.51 (1.41 −1.62) 1.98 (1.64 −2.39) 1.90 (1.55 −2.28)
 Missing 0.60 (0.54 −0.67) 0.73 (0.64 −0.82) 0.26 (0.24 −0.28) 0.61 (0.56 −0.67) 1.21 (1.02 −1.44) 1.24 (1.03 −1.49)
Smoking
 Non-Smoker Ref Ref Ref Ref Ref Ref
 Ex-Smoker 1.62 (1.47 −1.78) 1.43 (1.29 −1.57) 1.82 (1.71 −1.93) 1.58 (1.49 −1.68) 1.47 (1.22 −1.78) 1.32 (1.10 −1.60)
 Smoker 1.69 (1.54 −1.84) 1.61 (1.46 −1.77) 2.19 (2.05 −2.33) 2.03 (1.90 −2.17) 2.54 (2.17 −2.95) 2.06 (1.79 −2.51)
 Missing 0.31 (0.24 −0.41) 0.48 (0.36 −0.64) 0.07 (0.06 −0.08) 0.12 (0.10 −0.14) 1.16 (0.95 −1.41) 1.19 (0.96 −1.47)
Patient level deprivation quintiles (IMD)
 1, least deprived Ref Ref Ref Ref Ref Ref
 2 0.95 (0.84 −1.07) 0.92 (0.81 −1.05) 0.87 (0.81 −0.93) 0.88 (0.82 −0.96) 1.33 (0.99 −1.77) 1.22 (0.92 −1.64)
 3 1.00 (0.88 −1.13) 0.93 (0.82 −1.05) 0.90 (0.83 −0.97) 0.92 (0.85 −1.00) 1.89 (1.40 −2.45) 1.56 (1.17 −2.07)
 4 0.98 (0.87 −1.11) 0.90 (0.79 −1.02) 0.78 (0.72 −0.84) 0.87 (0.79 −0.95) 2.67 (2.06 −3.49) 2.18 (1.67 −2.87)
 5, most deprived 0.96 (0.85 −1.09) 0.88 (0.77 −1.00) 0.88 (0.82 −0.96) 0.90 (0.83 −0.99) 2.49 (1.89 −3.19) 1.77 (1.34 −2.34)
 Missing 0.90 (0.81 −1.00) 0.86 (0.77 −0.96) 0.80 (0.74 −0.88) 0.90 (0.82 −0.99) 1.82 (1.36 −2.44) 1.65 (1.23 −2.23)
  1. a South Asian for CPRD, Asian for SAIL and SMR
  2. Adjusted for maternal age, gravidity, ethnicity, BMI, smoking status, patient level IMD
  3. BMI body mass index, CI confidence intervals, CPRD Clinical Practice Research Datalink, IMD Index of Multiple Deprivation, OR odds ratio, Ref reference group, SAIL The Secure Anonymized Information Linkage databank, SMR Scottish Morbidity Records