Table 2 Logistic regression for pre-existing multimorbidity by women’s characteristics
Characteristics | CPRD (England), n = 13,075 | SAIL (Wales), n = 27,782 | SMR (Scotland), n = 6099 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |||||||||||||
Age categories (5 yearly) | ||||||||||||||||||
15–19 | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
20–24 | 1.60 | (1.34 | −1.90) | 1.17 | (0.97 | − 1.42) | 1.64 | (1.45 | − 1.85) | 1.10 | (0.96 | −1.26) | 1.48 | (1.11 | −1.94) | 1.42 | (1.05 | − 1.92) |
25–29 | 1.80 | (1.52 | −2.12) | 1.21 | (1.01 | − 1.45) | 1.93 | (1.72 | −2.17) | 1.21 | (1.06 | −1.39) | 1.36 | (1.02 | −1.81) | 1.45 | (1.07 | − 1.95) |
30–34 | 1.84 | (1.56 | −2.17) | 1.26 | (1.05 | − 1.52) | 2.19 | (1.94 | −2.46) | 1.36 | (1.19 | −1.56) | 1.18 | (0.89 | −1.58) | 1.32 | (0.97 | −1.80) |
35–39 | 1.95 | (1.64 | −2.32) | 1.28 | (1.06 | −1.56) | 2.54 | (2.24 | − 2.89) | 1.64 | (1.42 | −1.90) | 1.23 | (0.90 | −1.69) | 1.37 | (0.97 | −1.93) |
40–44 | 2.55 | (2.04 | −3.20) | 1.61 | (1.26 | −2.06) | 3.19 | (2.63 | −3.88) | 2.20 | (1.77 | −2.73) | 1.04 | (0.62 | −1.75) | 1.18 | (0.68 | −2.04) |
45–49 | 2.98 | (1.74 | −5.11) | 1.81 | (1.04 | −3.17) | 3.88 | (1.94 | −7.76) | 4.11 | (1.83 | −9.26) | 1.56 | (0.42 | −5.87) | 1.67 | (0.45 | −6.93) |
Gravidity | ||||||||||||||||||
1 | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
2 | 1.07 | (0.97 | −1.18) | 0.98 | (0.89 | −1.08) | 1.20 | (1.14 | −1.26) | 1.03 | (0.97 | −1.09) | 1.09 | (0.92 | −1.30) | 1.03 | (0.86 | −1.23) |
3 | 1.35 | (1.22 | −1.50) | 1.18 | (1.06 | −1.32) | 1.51 | (1.40 | −1.63) | 1.16 | (1.07 | −1.27) | 1.30 | (1.07 | −1.58) | 1.17 | (0.95 | −1.43) |
4 | 1.52 | (1.35 | −1.72) | 1.30 | (1.15 | −1.48) | 1.89 | (1.67 | −2.15) | 1.39 | (1.21 | −1.60) | 1.77 | (1.41 | −2.21) | 1.49 | (1.17 | −2.01) |
≥ 5 | 2.11 | (1.9 | −2.35) | 1.68 | (1.50 | −1.89) | 2.73 | (2.27 | −3.29) | 1.81 | (1.48 | −2.22) | 2.70 | (2.21 | −3.34) | 2.19 | (1.75 | −2.76) |
Missing | – | – | – | – | – | – | – | – | – | – | – | – | 1.75 | (0.18 | −16.88) | 1.31 | (0.13 | −13.43) |
Ethnicity | ||||||||||||||||||
Asian /South Asiana | 0.60 | (0.52 | −0.69) | 0.66 | (0.56 | −0.77) | 0.48 | (0.39 | −0.59) | 0.53 | (0.43 | −0.66) | 0.44 | (0.26 | −0.75) | 0.51 | (0.29 | −0.87) |
Black | 0.76 | (0.63 | −0.91) | 0.73 | (0.61 | − 0.89) | 0.31 | (0.22 | − 0.43) | 0.31 | (0.22 | −0.45) | 0.78 | (0.27 | −2.31) | 0.86 | (0.29 | −2.58) |
Mixed | 0.88 | (0.67 | −1.16) | 0.95 | (0.72 | −1.26) | 0.78 | (0.54 | −1.11) | 0.86 | (0.59 | −1.27) | – | – | – | – | – | – |
Other | 0.55 | (0.44 | − 0.70) | 0.61 | (0.48 | − 0.77) | 0.31 | (0.23 | − 0.42) | 0.33 | (0.24 | − 0.45) | 0.66 | (0.38 | −1.15) | 0.59 | (0.33 | −1.05) |
White | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
Missing | 0.85 | (0.78 | −0.93) | 0.94 | (0.86 | −1.03) | 0.61 | (0.58 | −0.65) | 0.74 | (0.70 | −0.78) | 0.62 | (0.51 | −0.75) | 0.63 | (0.52 | −0.77) |
BMI (kg/m2) | ||||||||||||||||||
Underweight (< 18.5) | 0.89 | (0.73 | −1.07) | 0.91 | (0.75 | −1.10) | 1.06 | (0.94 | −1.19) | 1.08 | (0.96 | −1.22) | 1.59 | (0.96 | −2.63) | 1.27 | (0.68 | −1.93) |
Normal Weight (18.5–24.9) | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
Overweight (25–29.9) | 1.20 | (1.10 | −1.31) | 1.16 | (1.05 | −1.27) | 1.19 | (1.11 | −1.27) | 1.17 | (1.09 | −1.25) | 1.31 | (1.06 | −1.62) | 1.33 | (0.75 | −2.16) |
Obese (30+) | 1.69 | (1.53 | −1.86) | 1.59 | (1.44 | −1.76) | 1.57 | (1.47 | −1.69) | 1.51 | (1.41 | −1.62) | 1.98 | (1.64 | −2.39) | 1.90 | (1.55 | −2.28) |
Missing | 0.60 | (0.54 | −0.67) | 0.73 | (0.64 | −0.82) | 0.26 | (0.24 | −0.28) | 0.61 | (0.56 | −0.67) | 1.21 | (1.02 | −1.44) | 1.24 | (1.03 | −1.49) |
Smoking | ||||||||||||||||||
Non-Smoker | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
Ex-Smoker | 1.62 | (1.47 | −1.78) | 1.43 | (1.29 | −1.57) | 1.82 | (1.71 | −1.93) | 1.58 | (1.49 | −1.68) | 1.47 | (1.22 | −1.78) | 1.32 | (1.10 | −1.60) |
Smoker | 1.69 | (1.54 | −1.84) | 1.61 | (1.46 | −1.77) | 2.19 | (2.05 | −2.33) | 2.03 | (1.90 | −2.17) | 2.54 | (2.17 | −2.95) | 2.06 | (1.79 | −2.51) |
Missing | 0.31 | (0.24 | −0.41) | 0.48 | (0.36 | −0.64) | 0.07 | (0.06 | −0.08) | 0.12 | (0.10 | −0.14) | 1.16 | (0.95 | −1.41) | 1.19 | (0.96 | −1.47) |
Patient level deprivation quintiles (IMD) | ||||||||||||||||||
1, least deprived | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – | Ref | – | – |
2 | 0.95 | (0.84 | −1.07) | 0.92 | (0.81 | −1.05) | 0.87 | (0.81 | −0.93) | 0.88 | (0.82 | −0.96) | 1.33 | (0.99 | −1.77) | 1.22 | (0.92 | −1.64) |
3 | 1.00 | (0.88 | −1.13) | 0.93 | (0.82 | −1.05) | 0.90 | (0.83 | −0.97) | 0.92 | (0.85 | −1.00) | 1.89 | (1.40 | −2.45) | 1.56 | (1.17 | −2.07) |
4 | 0.98 | (0.87 | −1.11) | 0.90 | (0.79 | −1.02) | 0.78 | (0.72 | −0.84) | 0.87 | (0.79 | −0.95) | 2.67 | (2.06 | −3.49) | 2.18 | (1.67 | −2.87) |
5, most deprived | 0.96 | (0.85 | −1.09) | 0.88 | (0.77 | −1.00) | 0.88 | (0.82 | −0.96) | 0.90 | (0.83 | −0.99) | 2.49 | (1.89 | −3.19) | 1.77 | (1.34 | −2.34) |
Missing | 0.90 | (0.81 | −1.00) | 0.86 | (0.77 | −0.96) | 0.80 | (0.74 | −0.88) | 0.90 | (0.82 | −0.99) | 1.82 | (1.36 | −2.44) | 1.65 | (1.23 | −2.23) |