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Table 1 Maternal characteristics of subjects in non-GDM and GDM groups before (period 1) and after (period 2) changes of GDM diagnostic criteria

From: Obstetric and neonatal outcomes of gestational diabetes mellitus in twin pregnancies according to changes in its diagnostic criteria from National Diabetes Data Group criteria to Carpenter and Coustan criteria: a retrospective cohort study

 

Period 1 (NDDG criteria)

Period 2 (C–C criteria)

Interaction test

P-value*

 

Non-GDM

(n = 607)

GDM

(n = 25)

P-value

Non-GDM

(n = 1,027)

GDM

(n = 105)

P-value

 Maternal age (year)

31.1 ± 3.8

33.9 ± 4.2

0.001

32.8 ± 3.6

34.1 ± 3.7

 < 0.001

0.068

 Maternal age ≥ 35 years

102 (16.8)

11 (44.0)

0.002

321 (31.3)

48 (45.7)

0.003

0.111

 Pre-pregnancy BMI (Kg/m2)

20.6 ± 2.7

22.6 ± 4.5

0.119

21.0 ± 3.0

22.3 ± 3.8

0.001

0.368

 Gestational weight gain (Kg)

17.6 ± 5.8

12.7 ± 4.9

 < 0.001

15.7 ± 6.2

12.3 ± 5.1

 < 0.001

0.293

 Multiparity

143 (23.6)

9 (36.0)

0.154

231 (22.5)

25 (23.8)

0.759

0.281

 History of PTD

19 (3.1)

4 (16.0)

0.010

35 (3.4)

6 (5.7)

0.264

0.099

 ART pregnancy

268 (44.2)

11 (44.0)

0.988

495 (48.3)

61 (58.1)

0.055

0.381

 Chorionicity

  

0.705

  

0.024

0.722

 Monoamnionic

5 (0.8)

0 (0)

 

2 (0.2)

1 (1.0)

  

 Monochorionic diamnionic

163 (26.9)

5 (20.0)

 

198 (19.3)

11 (10.5)

  

 Dichorionic diamnionic

430 (70.8)

19 (76.0)

 

827 (80.5)

93 (88.6)

  

 Unknown

9 (1.5)

1 (4.0)

 

0 (0)

0 (0)

  

 Insulin treatment

0 (0)

5 (20.0)

NA

0 (0)

24 (23.1)

NA

NA

  1. Data expressed as mean ± standard deviation or number (%). NDDG National Diabetes Data Group, C–C Carpenter and Coustan, GDM gestational diabetes mellitus, PTD preterm delivery, ART assisted reproductive technology, NA not analyzable. *logistic model for categorical variables and regression model for continuous variables