Table 1 Descriptive statistics for women of childbearing age prescribed valproate in 2004 and 2018
Year n (%) | |||
|---|---|---|---|
2004 | 2018 | Chi-square | |
N | 1639 | 1149 | P value |
Demographics | |||
Age range | 0.001 | ||
Under 20 | 158 (9.6) | 133 (11.6) | |
20–29 | 378 (23.1) | 238 (20.7) | |
30–39 | 607 (37.0) | 366 (31.9) | |
Over 40 | 496 (30.3) | 412 (35.9) | |
IMD | NS | ||
1 (most deprived) | 355 (22.2) | 285 (25.4) | |
2 | 322 (20.1) | 224 (19.9) | |
3 | 294 (18.4) | 205 (18.3) | |
4 | 332 (20.7) | 213 (19.0) | |
5 (least deprived) | 299 (18.7) | 196 (17.5) | |
Ethnicity | < 0.001 | ||
White | 966 (58.9) | 842 (73.3) | |
Asian | 48 (2.9) | 62 (5.4) | |
Black | 22 (1.3) | 24 (2.1) | |
Mixed | 10 (0.6) | 17 (1.5) | |
Other | 4 (0.2) | 8 (0.7) | |
Missing | 589 (35.9) | 196 (17.1) | |
Smoking | < 0.001 | ||
Non-smoker | 617 (37.6) | 465 (40.5) | |
Current smoker | 557 (34.0) | 270 (23.5) | |
Former smoker | 233 (14.2) | 316 (27.5) | |
Missing | 232 (14.2) | 98 (8.5) | |
Indications | |||
Epilepsy | 1149 (70.1) | 715 (62.2) | < 0.001 |
Bipolar Disorder | 188 (11.5) | 181 (15.8) | 0.001 |
Migraine | 118 (7.2) | 85 (7.4) | NS |
Epilepsy and Migraine | 165 (10.1) | 116 (10.1) | NS |
Epilepsy and Bipolar disorder | 46 (2.8) | 30 (2.6) | NS |
Bipolar and Migraine | 60 (3.7) | 54 (4.7) | NS |