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Table 3 Outcomes of two groups for endometrial preparation

From: Pretreatment with a GnRH agonist and hormone replacement treatment protocol could not improve live birth rate for PCOS women undergoing frozen-thawed embryo transfer cycles

 

Matched Cohort (n = 1038) a

Entire Cohort (n = 1638) b

Variable

HRT (n = 514)

GnRHa+HRT (n = 514)

P-value

HRT (n = 1115)

GnRHa+HRT (n = 523)

P-value

Duration of endometrial preparation (days)

11.00 ± 3.74

11.62 ± 3.54

0.010

11.35 ± 3.77

11.61 ± 3.58

0.470

Endometrial thickness on the day of progesterone administration (mm)

10.00 ± 1.62

10.18 ± 1.55

0.030

9.76 ± 1.54

10.18 ± 1.55

< 0.001

Triple-line endometrial pattern (%)

  

0.144

  

0.008

  A

55 (10.70%)

74 (14.40%

 

103 (9.24%)

75 (14.34%)

 

  B

429 (83.46%)

405 (78.79%)

 

931 (83.50%)

413 (78.97%)

 

  C

30 (5.84%)

35 (6.81%)

 

81 (7.26%)

35 (6.69%)

 

Embryo stage (n, %)

  

0.316

  

< 0.001

  Cleavage stage

157 (30.54%)

172 (33.46%)

 

282 (25.29%)

174 (33.27%)

 

  Blastocyst stage

357 (69.46%)

342 (66.54%)

 

833 (74.71%)

349 (66.73%)

 

Number of transferred embryos (n, %)

1.75 ± 0.46

1.76 ± 0.45

0.493

1.74 ± 0.46

1.76 ± 0.45

0.428

Number of the available embryos (n, %)

9.68 ± 5.63

8.70 ± 4.68

0.003

10.08 ± 5.26

8.69 ± 4.70

< 0.001

Number of good quality embryos transferred (n, %)

1.14 ± 0.77

1.06 ± 0.78

0.117

1.15 ± 0.75

1.06 ± 0.78

0.025

Clinical pregnancy rate (n, %)

363 (70.62%)

387 (75.29%)

0.092

811 (72.74%)

394 (75.33%)

0.266

Preterm birth rate (n, %)

67 (13.04%)

104 (20.23%)

0.002

157 (14.08%)

105 (20.08%)

0.002

Miscarriage rate (n, %)

71 (13.81%)

73 (14.20%)

0.857

159 (14.26%)

73 (13.96%)

0.870

Ectopic pregnancy rate (n, %)

1 (0.19%)

2 (0.39%)

0.563

4 (0.36%)

2 (0.38%)

0.941

Live birth rate (n, %)

288 (56.03%)

309 (60.12%)

0.073

619 (55.52%)

316 (60.42%)

0.062

Birth weight (kg)

3.10 ± 0.71

3.06 ± 0.68

0.645

3.07 ± 0.72

3.07 ± 0.68

0.914

Fetal sex (n, %)

  

0.583

  

0.783

  Female

137 (50.18%)

149 (47.91%)

 

290 (46.85%)

152 (47.80%)

 

  Male

136 (49.82%)

162 (52.09%)

 

329 (53.15%)

166 (52.20%)

 
  1. χ2 test, Student’s t test
  2. aPropensity score-matched cohort, b before propensity score matching