Matched Cohort (n = 1038) a | Entire Cohort (n = 1638) b | |||||
---|---|---|---|---|---|---|
Variable | HRT (n = 514) | GnRHa+HRT (n = 514) | P-value¶ | HRT (n = 1115) | GnRHa+HRT (n = 523) | P-value¶ |
Duration of endometrial preparation (days) | 11.00 ± 3.74 | 11.62 ± 3.54 | 0.010 | 11.35 ± 3.77 | 11.61 ± 3.58 | 0.470 |
Endometrial thickness on the day of progesterone administration (mm) | 10.00 ± 1.62 | 10.18 ± 1.55 | 0.030 | 9.76 ± 1.54 | 10.18 ± 1.55 | < 0.001 |
Triple-line endometrial pattern (%) | 0.144‡ | 0.008‡ | ||||
A | 55 (10.70%) | 74 (14.40% | 103 (9.24%) | 75 (14.34%) | ||
B | 429 (83.46%) | 405 (78.79%) | 931 (83.50%) | 413 (78.97%) | ||
C | 30 (5.84%) | 35 (6.81%) | 81 (7.26%) | 35 (6.69%) | ||
Embryo stage (n, %) | 0.316‡ | < 0.001‡ | ||||
Cleavage stage | 157 (30.54%) | 172 (33.46%) | 282 (25.29%) | 174 (33.27%) | ||
Blastocyst stage | 357 (69.46%) | 342 (66.54%) | 833 (74.71%) | 349 (66.73%) | ||
Number of transferred embryos (n, %) | 1.75 ± 0.46 | 1.76 ± 0.45 | 0.493 | 1.74 ± 0.46 | 1.76 ± 0.45 | 0.428 |
Number of the available embryos (n, %) | 9.68 ± 5.63 | 8.70 ± 4.68 | 0.003 | 10.08 ± 5.26 | 8.69 ± 4.70 | < 0.001 |
Number of good quality embryos transferred (n, %) | 1.14 ± 0.77 | 1.06 ± 0.78 | 0.117 | 1.15 ± 0.75 | 1.06 ± 0.78 | 0.025 |
Clinical pregnancy rate (n, %) | 363 (70.62%) | 387 (75.29%) | 0.092‡ | 811 (72.74%) | 394 (75.33%) | 0.266‡ |
Preterm birth rate (n, %) | 67 (13.04%) | 104 (20.23%) | 0.002‡ | 157 (14.08%) | 105 (20.08%) | 0.002‡ |
Miscarriage rate (n, %) | 71 (13.81%) | 73 (14.20%) | 0.857‡ | 159 (14.26%) | 73 (13.96%) | 0.870‡ |
Ectopic pregnancy rate (n, %) | 1 (0.19%) | 2 (0.39%) | 0.563‡ | 4 (0.36%) | 2 (0.38%) | 0.941‡ |
Live birth rate (n, %) | 288 (56.03%) | 309 (60.12%) | 0.073‡ | 619 (55.52%) | 316 (60.42%) | 0.062‡ |
Birth weight (kg) | 3.10 ± 0.71 | 3.06 ± 0.68 | 0.645 | 3.07 ± 0.72 | 3.07 ± 0.68 | 0.914 |
Fetal sex (n, %) | 0.583‡ | 0.783‡ | ||||
Female | 137 (50.18%) | 149 (47.91%) | 290 (46.85%) | 152 (47.80%) | ||
Male | 136 (49.82%) | 162 (52.09%) | 329 (53.15%) | 166 (52.20%) |