Stress, anxiety, and depression in infertile couples are not associated with a first IVF or ICSI treatment outcome

Table 3 Conditional logistic Regression Analysis of psychological distress symptoms on pregnancy rate of first IVF or ICSI cycle among 450 women

Psychological distress	N	No. of non-pregnancy (%)	Crude OR^a (95%CI)	Adjusted OR^b (95%CI)	Adjusted OR^c (95%CI)
Anxiety
No	439	148 (33.7)	1.00	1.00	1.00
Yes	11	2 (18.2)	0.44 (0.10-2.06)	0.46 (0.10-2.20)	0.27 (0.03-2.33)
Depression
No	388	129 (33.2)	1.00	1.00	1.00
Yes	62	21 (33.9)	1.03 (0.57-1.85)	0.93 (0.51-1.70)	0.88 (0.46-1.68)
Psychological distress^d
Norm	387	129 (33.3)	1.00	1.00	1.00
One symptom (Depression/Anxiety)	53	19 (35.8)	1.11 (0.60-2.06)	0.99 (0.53-1.85)	0.95 (0.49-1.84)
Two symptoms (Depression and Anxiety)	10	2 (20.0)	0.51 (0.11-2.42)	0.52 (0.11-2.54)	0.29 (0.03-2.63)

^aUnivariable conditional logistic regression analyses of psychological distress level on pregnancy rate of first IVF or ICSI cycle
^bModel 1: Multivariable conditional logistic regression analyses were adjusted for female pre-treatment BMI, educational attainment, occupation, household income, infertility factor, duration of infertility
^cModel 2: Multivariable conditional logistic regression analyses were adjusted for female pre-treatment BMI, educational attainment, occupation, household income, infertility factor, duration of infertility, prior history of pregnancy loss, alcohol use, sleep quality, exercise, female and male smoking before the start of treatment
^dNorm was defined as women without any symptom including depression, anxiety. One symptom was defined as women with any symptom including depression or anxiety. Two symptoms were defined as women with depression and anxiety

ISSN: 1471-2393