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Table 1 Demographic data for total MAMAS participants

From: A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers

Demographics

20–30 Years (n = 154)

35–39 Years (n = 222)

≥40 Years (n = 152)

P value Overall

P value Multiple Comparisons

Maternal age

26 (20–30)

37 (35–39)

42 (40–49)

  

Paternal Age a

29 (18–48)

38 (21–50)

43 (24–60)

< 0.001

†¶Δ < 0.0001

BMI (kg/m2) a

23.8 (18.7–29.9)

24.1 (18.5–29.5)

24.9 (19.0–29.9)

1 missing value

0.0026

†0.10, ¶0.0004, Δ0.008

European Ethnicityb

90% (138)

87% (191)

95% (144)

0.08

 

Marital Status b

 Single

5% (7)

2% (5)

5% (8)

0.001

†< 0.001, ¶0.15, Δ0.08

 Married/CP

45% (69)

66% (146)

55% (83)

  

 Partner

51% (78)

31% (69)

39% (60)

  

 Other

0% (0)

1% (1)

1% (1)

  

Occupation b

 Employed – Full Time

55% (84)

49% (109)

59% (89)

0.51

 

 Employed – Part Time

26% (40)

32% (72)

26% (40)

  

 Unemployed

18% (28)

16% (35)

14% (21)

  

 Unknown

1% (2)

3% (6)

1% (2)

  

Smoking Status b

 Non-smoker

71% (110)

74% (165)

81% (123)

0.056

 

 Current

11% (17)

5% (12)

3% (5)

  

 Ex-smoker

18% (27)

20% (45)

16% (24)

  

Housing b

 Owns

45% (70)

73% (163)

84% (127)

< 0.001

†¶ p < 0.001,Δ0.023

IMD a

19.09

16.11

15.54

0.25

 

 Score

(2.28–71.95)

4 missing values

(1.94–76.09)

7 missing values

(1.94–69.63)

13 missing values

  

Parity b

 Primiparous

49% (76)

28% (62)

34% (52)

< 0.001

† < 0.001, 0.001, Δ0.092

 Parous

51% (86)

72% (160)

66% (100)

  

Previous APO b,c

22% (17)

32% (51)

22% (22)

0.12

 

 FGR c

13% (10)

21% (33)

11% (11)

0.09

 

 Stillbirth c

0% (0)

3% (4)

4% (1)

0.52

 

Previous ART b

< 1% (1)

8% (18)

18% (28)

< 0.001

†0.001, ¶ < 0.001, Δ0.004

ART b

< 1% (1)

9% (21)

14% (22)

0.004

†0.001, ¶ < 0.001, Δ0.005

 Hormonal

< 1% (1)

2% (5)

1% (2)

  

 IVF

0% (0)

6% (13)

7% (10)

  

 IVF - Donor

0% (0)

< 1%(1)

7% (10)

  

 IUI

0% (0)

1% (2)

0% (0)

  
  1. Data are mean (range) or percentage (number). BMI Body mass index, CP Civil partnership, IMD Index of multiple deprivation, APO Adverse pregnancy outcome, ART Assisted reproductive therapies, IVF In vitro fertilisation, Donor = egg and/or sperm, IUI Intrauterine insemination. Statistical differences are aKruskal-Wallis with Dunn’s multiple comparisons or b Fishers exact test. c expressed as percentage of parous women. When overall p > 0.05, multiple comparisons p values are reported († 20–30 vs. 35–39 years, ¶ 20–30 vs ≥40 years, Δ 35–39 vs. ≥40 years). Significant differences are highlighted with bold p values