From: The role of complement factor H in gestational diabetes mellitus and pregnancy
 | GDM (n = 80) | Non-GDM (n = 317) |  |
---|---|---|---|
Parametersa | Median (IQR) or mean ± SD or % | Median (IQR) or mean ± SD or % | P valueb |
Gestational age at the first prenatal visit, week | 14.00 (2.75) | 13.00 (3.00) | 0.292†|
Age, years | 29.00 (5.00) | 27.00 (5.00) | 0.012†|
Pre-pregnancy BMI, kg/m2 | 21.70 (4.33) | 20.80 (3.65) | < 0.001†|
BMI, kg/m2 | 21.98 (4.93) | 20.90 (3.75) | < 0.001†|
SBP, mmHg | 118.00 (16.75) | 115.00 (14.00) | 0.215†|
DBP, mmHg | 75.00 (11.00) | 74.00 (12.50) | 0.502†|
Family History of diabetes, % | 10 | 4.7 | 0.125# |
GA, % | 12.08 ± 1.91 | 11.92 ± 1.55 | 0.422* |
FPG, mmol/L | 4.85 (0.60) | 4.70 (0.50) | < 0.001†|
HbA1c, % | 5.20 (0.40) | 5.10 (0.30) | < 0.001†|
ALT, units/L | 14.50 (16.50) | 12.00 (11.00) | 0.024†|
AST, units/L | 16.00 (7.60) | 16.00 (5.30) | 0.940†|
γ-GT, units/L | 11.50 (8.30) | 11.00 (8.30) | 0.425†|
ALP, units/L | 45.00 (15.75) | 46.00 (14.00) | 0.488†|
TB, μmol/L | 8.20 (4.58) | 7.90 (3.75) | 0.539†|
ALB, g/L | 42.10 (3.05) | 42.100 (3.65) | 0.872†|
BUN, mmol/L | 2.80 (0.90) | 2.70 (0.80) | 0.458†|
Cr, μmol/L | 44.00 (8.00) | 44.00 (8.00) | 0.197†|
UA, μmol/L | 220.50 (62.00) | 204.00 (60.00) | 0.004†|
TG, mmol/L | 1.49 (0.79) | 1.295 (0.65) | 0.007†|
TC, mmol/L | 4.62 ± 0.79 | 4.42 ± 0.78 | 0.042* |
LDL-C, mmol/L | 2.52 ± 0.67 | 2.36 ± 0.66 | 0.051* |
CFH, μg/ml | 280.02 (58.60) | 264.20 (68.77) | 0.014†|
GDM screening 75 g OGTT | |||
Gestational age at 75 g OGTT, week | 25.00 (2.00) | 25.00 (1.00) | 0.777†|
Glucose 0 h, mmol/L | 5.15 (0.70) | 4.50 (0.50) | < 0.001†|
Glucose 1 h, mmol/L | 9.79 ± 1.82 | 7.24 ± 1.39 | < 0.001* |
Glucose 2 h, mmol/L | 7.95 (2.15) | 6.31 (1.56) | < 0.001†|
Pregnancy outcomes | |||
Gestational age at delivery, week | 39.00 (1.00) | 39.00 (1.00) | 0.100†|
Caesarean section, % | 48.8 | 42.3 | 0.296# |
PROM, % | 11.3 | 11.4 | 0.979# |
Estimated blood loss at delivery, ml | 300.00 (90.00) | 300.00 (100.00) | 0.71†|
Macrosomia, % | 11.0 | 4.4 | 0.038# |
Apgar score | 10.00 (0.00) | 10.00 (0.00) | 0.291†|