Skip to main content

Table 3 Associations between lifestyle behaviours and adverse pregnancy outcome

From: Associations between periconceptional lifestyle behaviours and adverse pregnancy outcomes

 

Composite (n=712)a

HDP (n=298)

GDM (n=184)

sPTB (n=127)

SGA (n=133)

Crude OR (95% CI)

Adjusted OR (95% CI)b

Crude (95% CI)

Adjusted (95% CI)b

Crude (95% CI)

Adjusted (95% CI)b

Crude (95% CI)

Adjusted (95% CI)b

Crude (95% CI)

Adjusted (95% CI)b

Pre-pregnancy BMI

 Underweight (<18.5 kg/m2)

1.18 (0.66-2.12)

1.22 (0.67 - 2.23)

0.43 (0.11-1.74)

0.44 (0.11-1.82)

0.86 (0.20-3.68)

0.92 (0.21-4.04)

1.07 (0.32-3.60)

1.10 (0.32-3.79)

2.65 (1.23-5.74)

2.64 (1.17-5.96)

 Normal weight (18.5-25 kg/m2)

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

 Overweight (25-30 kg/m2)

1.65 (1.35-2.03)

1.61 (1.31 - 1.99)

2.18 (1.5-2.89)

2.17 (1.63-2.89)

2.59 (1.77-3.80)

2.38 (1.60-3.54)

1.01 (0.63-1.61)

0.99 (0.61-1.60)

0.89 (0.52-1.51)

0.84 (0.48-1.46)

 Obese (>30 kg/m2)

2.96 (2.31-3.80)

2.85 (2.20 - 3.68)

3.83 (2.72-5.38)

3.80 (2.68-5.40)

7.18 (4.74 - 10.89)

6.85 (4.39-10.71)

0.85 (0.37-1.93)

0.82 (0.36 - 1.85)

1.29 (0.67-2.50)

1.16 (0.59 - 2.31)

Smoking

 no preconception use

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

 smoked, quit prenatal

1.48 (1.16-1.87)

1.32 (1.03 - 1.70)

1.52 (1.08-2.14)

1.33 (0.94-1.90)

1.33 (0.87-2.05)

1.24 (0.79-1.95)

1.93 (1.19-3.13)

1.76 (1.05-2.93)

1.38 (0.75-2.53)

1.14 (0.59-2.21)

 smoked, did not quit prenatal

1.41 (1.03-1.94)

1.23 (0.86-1.75)

1.03 (0.61-1.72)

0.88 (0.52-1.50)

1.17 (0.64-2.13)

1.05 (0.55-2.02)

1.91 (1.04-3.49)

1.83 (0.91-3.65)

2.47 (1.45-4.21)

1.91 (1.05 - 1.15)

Alcohol consumption

 no preconception use

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

 used alcohol, quit prenatal

0.85 (0.70-1.02)

0.84 (0.69 - 1.03)

0.94 (0.72-1.24)

0.87 (0.65-1.15)

0.51 (0.37-0.71)

0.65 (0.46-0.93)

1.03 (0.71-1.51)

0.89 (0.60-1.34)

0.88 (0.60-1.31)

0.88 (0.57-1.36)

 used alcohol, did not quit prenatalc

0.58 (0.17-1.92)

0.57 (0.17-1.94)

_

_

_

_

_

_

_

_

Folic acid usede

 no preconception use

1.28 (0.98-1.65)

1.28 (0.97-1.69)

1.26 (0.87-1.81)

1.48 (1.00-2.18)

1.33 (0.84-2.11)

0.97 (0.58-1.62)

1.02 (0.54-1.92)

1.18 (0.59-2.35)

1.51 (0.86-2.63)

1.41 (0.75-2.64)

 only prenatal

0.96 (0.79-1.17)

1.01 (0.82-1.25)

0.85 (0.63-1.14)

0.95 (0.70-1.31)

0.93 (0.65-1.33)

0.96 (0.66-1.40)

0.99 (0.65-1.50)

1.10 (0.70-1.71)

1.17 (0.77-1.76)

1.26 (0.81-1.96)

 preconception and prenatal

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

Vitamin useef

 no preconception use

1.19 (0.96-1.48)

1.19 (0.95-1.50)

1.26 (0.93-1.72)

1.36 (0.99-1.87)

1.05 (0.71-1.55)

0.91 (0.60-1.38)

0.92 (0.58-1.45)

0.95 (0.59-1.54)

1.53 (0.94-2.47)

1.48 (0.88-2.49)

 only prenatal

0.90 (0.72-1.11)

0.89 (0.72-1.12)

0.85 (0.61-1.17)

0.86 (0.61-1.20)

0.95 (0.64-1.39)

0.99 (0.67-1.46)

0.78 (0.50-1.22)

0.78 (0.49-1.22)

0.87 (0.53-1.44)

0.87 (0.53-1.46)

 preconception and prenatal

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

Fruit

          

 daily fruit intake < 2 pieces

0.91 (0.76-1.08)

0.84 (0.70-1.01)

0.87 (0.73-1.14)

0.79 (0.60-1.04)

0.96 (0.69-1.32)

0.92 (0.66-1.29)

1.08 (0.74-1.59)

0.96 (0.64-1.44)

0.84 (0.58-1.21)

0.72 (0.49-1.06)

 daily fruit intake ≥ 2 pieces

ref

ref

ref

ref

ref

ref

ref

ref

ref

ref

  1. HDP hypertensive disorders in pregnancy, GDM gestational diabetes, sPTB spontaneous preterm birth, SGA small for gestational age, OR odds ratio, CI confidence interval
  2. acomposite outcome: women with one of the following complications; HDP, GDM, sPTB, SGA or fetal death.
  3. badjusted for non-modifiable factors (age, ethnicity, educational level, nulliparity, spontaneous conception)
  4. cn was too small in total population (n=28) to calculate odds ratios
  5. dincluding multivitamin use
  6. ewomen using multivitamin were categorized in both ‘folic acid use’ and ‘vitamin use’
  7. fvitamin C, vitamin D, calcium or multivitamin use