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Table 2 Demographics and lifestyle behaviours of study participants stratified by pregnancy outcome

From: Associations between periconceptional lifestyle behaviours and adverse pregnancy outcomes

 

Cohort

Uncomplicated

Adverse pregnancy outcome

  

Composite

HDP

GDM

sPTB

SGA

n=3684

n=2972 (80.7)

n=712 (19.3)

n = 298 (8.1)

n=184 (5.0)

n=127 (3.4)

n=133 (3.6)

Age (years)

30.8 (28.0-33.6)

30.8 (27.9-33.6)

30.8 (28.2 -33.7)

30.3 (27.6-32.9)

31.8 (29.7-34.8)*

30.6 (28.2-32.6)

30.6 (28.0-33.9)

Ethnicity

 Caucasian

3330 (90.4)

2706 (91.0)

624 (87.6)

277 (93.0)

144 (78.3)

117 (92.1)

111 (83.5)

 Non-Caucasian

354 (9.6)

266 (9.0)

88 (12.4)*

21 (7.0)

40 (21.7)

10 (7.9)

22 (16.5)*

Educational level

 Low

279 (7.6)

213 (7.2)

66 (9.3)*

20 (6.7)

18 (9.8)

11 (8.7)

20 (15.0)*

 Medium

1274 (34.6)

995 (33.5)

279 (39.3)*

124 (41.6)*

82 (44.6)*

47 (37.0)

49 (36.8)

 High

2131 (57.8)

1764 (59.3)

367 (51.4)

154 (51.7)

84 (45.7)

69 (54.3)

64 (48.2)

Parity

 Nullipara

1643 (44.6)

1224 (41.2)

418 (58.8)*

189 (63.4)*

73 (39.7)

86 (67.7)*

34 (25.6)*

 Multipara

2041 (55.4)

1748 (58.8)

293 (41.2)

109 (36.6)

110 (59.8)

41 (32.3)

99 (74.4)

Mode of conception

 Spontaneous conception

3429 (93.1)

2791 (93.9)

638 (89.6)

261 (87.6)

155 (84.2)

116 (91.4)

120 (90.2)

 Non- spontaneous conception

255 (6.9)

181 (6.1)

74 (10.4)*

37 (12.4)*

29 (15.8)*

11 (8.7)

13 (9.8)

Pre-pregnancy BMI

 Underweight (<18.5 kg/m2)

99 (2.7)

81 (2.7)

18 (2.5)*

2 (0.7)

2 (1.1)

4 (3.1)

9 (6.8)*

 Normal weight (18.5-25 kg/m2)

2367 (64.3)

2001 (67.4)

367 (51.6)

137 (45.9)

67 (36.4)

86 (67.7)

86 (64.6)

 Overweight (25-30 kg/m2)

852 (23.1)

654 (22.0)

198 (27.8)*

97 (32.6)*

57 (31.0)*

28 (22.0)

25 (18.8)

 Obese (>30 kg/m2)

366 (9.9)

236 (7.9)

129 (18.1)*

62 (20.8)*

57 (31.0)*

9 (7.1)

13 (9.8)

Smoking

 No preconception smoking

2913 (79.0)

2388 (80.3)

526 (73.8)

224 (75.2)

140 (76.1)

86 (67.7)

92 (69.2)

 Smoked, quit prenatal

492 (13.4)

371 (12.5)

120 (16.9)*

53 (17.8)

29 (15.8)

26 (20.5)*

20 (15.0)*

 Smoked, did not quit prenatal

279 (7.6)

213 (7.2)

66 (9.3)

21 (7.0)

15 (8.2)

15 (11.8)*

21 (15.8)

Alcohol use

 No preconception use

1440 (39.1)

1138 (38.3)

302 (42.4)

119 (39.9)

101 (54.9)

48 (37.8)

55 (41.4)

 Used alcohol, quit prenatal

2216 (60.1)

1810 (60.9)

406 (57.0)

178 (59.7)

83 (45.1)*

79 (62.2)

76 (57.1)

 Used alcohol, did not quit prenatal

28 (0.8)

24 (0.8)

4 (0.6)

1 (0.4)

0 (0)

0 (0)

2 (1.5)

Folic acid useb (incl. multivitamin)

 No preconception use

430 (11.7)

330 (11.1)

99 (13.9)

42 (14.1)

27 (14.7)

15 (11.8)

20 (15.0)

 Only prenatal

1077 (29.2)

879 (29.6)

198 (27.8)

77 (25.8)

50 (27.2)

37 (29.1)

42 (31.6)

 Preconception and prenatal

2177 (59.1)

1763 (59.3)

415 (58.3)

179 (60.1)

107 (58.2)

75 (59.1)

71 (53.4)

Vitamin useb

 No preconception use

1276 (34.6)

998 (33.6)

279 (39.2)

123 (41.3)

65 (35.3)

44 (34.6)

61 (45.8)

 Only prenatal

1405 (38.1)

1161 (39.0)

243 (34.1)

96 (32.2)

68 (37.0)

44 (34.6)

40 (30.1)

 Preconception and prenatal

1003 (27.3)

813 (27.4)

190 (26.7)

79 (26.5)

51 (17.7)

39 (30.7)

32 (24.1)

Fruit

 Daily fruit intake < 2 pieces

1409 (38.2)

1124 (37.8)

285 (40.0)

122 (40.9)

71 (38.6)

46 (36.2)

56 (42.1)

 Daily fruit intake ≥ 2 pieces

2275 (61.8)

1849 (62.2)

427 (60.0)

176 (59.1)

112 (60.9)

81 (63.8)

77 (57.9)

  1. values are presented as median (IQR) or n (%)
  2. participants can have more than 1 adverse pregnancy outcome therefore the numbers do not add up
  3. HDP hypertensive disorders in pregnancy, GDM gestational diabetes, sPTB spontaneous preterm birth, SGA small for gestational age
  4. *differs significantly from the uncomplicated group based on logistic regression analysis, p<0.05
  5. acomposite outcome: women with one of the following complications; HDP, SGA, GDM, sPTB or fetal death
  6. bwomen using multivitamin were categorized in both ‘folic acid use’ and ‘vitamin use’