Table 1 Characteristics of included studies for prevalence of neural tube defects in Africa
From: Magnitude and determinants of neural tube defect in Africa: a systematic review and meta-analysis
Authors | year | Country | Design | Setting | sample size | number of NTD | Prevalence per 10,000 | SB per 10,000 | Anecephaly per 10,000 | Risk of bias |
|---|---|---|---|---|---|---|---|---|---|---|
Abbey et al. [25] | 2017 | Nigeria | cross-sectional | Hospital based | 7670 | 28 | 36.51 | 31.29 | 5.22 | Medium |
Genti et al. [29] | 2015 | Ethiopia | cross-sectional | Hospital based | 45,951 | 156 | 33.95 | 11.09 | 15.23 | Medium |
Ahuka et al. [43] | 2006 | D.Congo | cross-sectional | Hospital based | 8824 | 9 | 10.19 | 6.79 | 3.39 | Medium |
Alhassan et al. [19] | 2017 | Ghana | cross-sectional | Hospital based | 35,426 | 57 | 16.09 | 5.93 | 0.85 | Medium |
Anyanwu [17] | 2020 | Nigeria | cross-sectional | Hospital based | 1456 | 4 | 27.47 | Â | Â | Medium |
Alem et al. [26] | 2018 | Ethiopia | cross-sectional | Hospital based | 14,903 | 195 | 130.84 | 64.42 | 66.43 | Low |
Buccimazza et al. [45] | 1994 | South Africa | cross-sectional | Hospital based | 516,252 | 606 | 11.74 | 1.67 | 0.91 | Medium |
Mumpe-Mwanja et al. [42] | 2019 | Uganda | cross-sectional | Hospital based | 69,766 | 72 | 10.32 | Â | Â | Medium |
Ekanem et al. [22] | 2008 | Nigeria | cross-sectional | Hospital based | 127,929 | 110 | 8.59 | 3.67 | 1.56 | Medium |
Ekwochi et al. [21] | 2017 | Nigeria | cross-sectional | Hospital based | 5830 | 6 | 10.29 | 6.86 | 3.43 | Low |
EL-Mogharabi et al. [12] | 2019 | Libiya | cross-sectional | Hospital based | 16,765 | 18 | 10.74 | 5.37 | 5.37 | Medium |
Estifanos et al. [36] | 2017 | Ertrea | cross-sectional | Hospital based | 39,803 | 185 | 46.48 | 6.03 | 17.34 | Medium |
Adane et al. [28] | 2018 | Ethiopia | cross-sectional | Hospital based | 19,650 | 103 | 52.41 | 29.01 | 3.56 | Medium |
Haucher et al. [46] | 2008 | Algeria | cross-sectional | Hospital based | 28,500 | 215 | 75.44 | 43.51 | 31.23 | Medium |
Aride et al. [20] | 1992 | Nigeria | cross-sectional | Hospital based | 5799 | 42 | 72.43 | 55.18 | 17.24 | Medium |
Laamiri et al. [53] | 2014 | Morocco | cross-sectional | Hospital based | 819,224 | 330 | 4.03 | 1.81 | 2.22 | Medium |
Nasri et al. [48] | 2014 | Tunisia | cross-sectional | Hospital based | 3,803,889 | 769 | 2.02 | 0.79 | 1.23 | Medium |
Mekonen et al. [34] | 2015 | Ethiopia | cross-sectional | Hospital based | 1516 | 20 | 131.93 | 125.33 | 6.59 | Medium |
Omar et al. [47] | 2016 | Sudan | cross-sectional | Hospital based | 36,785 | 103 | 28.00 | 19.30 | 8.69 | Low |
Radouani et al. [48] | 2015 | Morocco | cross-sectional | Hospital based | 60,017 | 80 | 13.33 | 5.17 | 8.16 | High |
Singh et al. [49] | 2000 | Libiya | cross-sectional | Hospital based | 16,186 | 18 | 11.12 | 10.50 | 0.62 | Medium |
Sorri et al. [31] | 2015 | Ethiopia | cross-sectional | Hospital based | 28,961 | 177 | 61.12 | 28.31 | 32.80 | Medium |
Taye et al. [33] | 2019 | Ethiopia | cross-sectional | Hospital based | 76,201 | 612 | 80.31 | 127.95 | 27.29 | Low |
Eka et al. [23] | 2016 | Nigeria | cross-sectional | Hospital based | 7329 | 72 | 98.24 | 66.86 | 13.64 | Low |
Gadafaw et al. [38] | 2017 | Ethiopia | cross-sectional | Hospital based | 8677 | 111 | 127.93 | 51.86 | 76.06 | Low |
Mitiku et al. [27] | 2017 | Ethiopia | Cross-sectional | Hospital based | 84 | 2 | 238.09 | Â | 238.09 | High |
Legese et al. [30] | 2019 | Ethiopia | cross-sectional | Hospital based | 876 | 6 | 68.49 | 22.83 | 45.66 | Low |
Nandi and Singh [24] | 2018 | Nigeria | cross-sectional | Hospital based | 10,163 | 22 | 21.64 | 15.74338 | 5.90 | Medium |
Taye et al. [32] | 2016 | Ethiopia | cross-sectional | Hospital based | 319,776 | 1010 | 31.58 | 10.19 | 1.13 | Low |