Progesterone levels on the human chorionic gonadotropin trigger day affect the pregnancy rates for embryos transferred at different stages of development in both general and selected IVF/ICSI populations

Table 3 Results for the various index/ratios involving the serum progesterone level on the hCG trigger day. Analysis between pregnant and not pregnant women, blastocyst or cleaved embryo transfers, and general or selected populations

Variables	Blastocyst Pregnancy	Blastocyst No pregnancy	p	Cleaved embryo Pregnancy	Cleaved embryo No pregnancy	p
General population
cycles: n	160	312		192	546
POI (ng/ml/oocyte)	0.092 ± 0.058	0.102 ± 0.068	NS	0.122 ± 0.072^c	0.141 ± 0.082^a	< 0.01
P:E2 (pg/ml/pg/ml)	0.42 ± 0.35	0.49 ± 0.32	< 0.05	0.49 ± 0.31	0.52 ± 0.32	NS
PFI (nmole/l/follicle)	0.78 ± 0.34^a	0.76 ± 0.42^a	NS	0.82 ± 0.38^a	1.15 ± 0.46^a	< 0.001
Selected population
cycles: n	105	194		131	247
POI (ng/ml/oocyte)	0.098 ± 0.064	0.100 ± 0.084	NS	0.105 ± 0.065^d	0.107 ± 0.072^b	NS
P:E2 (pg/ml/pg/ml)	0.45 ± 0.36	0.48 ± 0.32	NS	0.46 ± 0.36	0.49 ± 0.38	NS
PFI (nmole/l/follicle)	1.08 ± 0.29^b	1.01 ± 0.41^b	NS	0.96 ± 0.24^b	1.43 ± 0.62^b	< 0.001

Legends: POI progesterone to oocyte index, P:E2 progesterone to estradiol ratio, PFI progesterone to follicle index, NS not significant
Statistical analysis: The “p” column indicates the difference between pregnant and not pregnant women in cases of blastocyst or cleaved embryo transfer
Difference between general and selected population (“top cycles”) for each index or ratio after blastocyst or cleaved embryo transfers: ^a-bp < 0.001, ^c-dp < 0.05

ISSN: 1471-2393