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Table 2 ART procedures of pregnancies carried to delivery following FET with different endometrial preparation protocols

From: Perinatal outcomes of neonates born from different endometrial preparation protocols after frozen embryo transfer: a retrospective cohort study

 

NC (N = 1921)

OS (N = 360)

HRT (N = 1583)

p

No. (%)

No. (%)

No. (%)

Characteristics of oocytes retrieval cycle

 COH protocol

  GnRH-agonist regimen

897 (46.69)

181 (50.28)

743 (46.94)

0.345

  GnRH-antagonist regimen

904 (47.06)

166 (46.11)

732 (46.24)

 

  Microflare protocol

100 (5.21)

11 (3.06)

85 (5.37)

 

  Others

20 (1.04)

2 (0.56)

23 (1.45)

 

 Type of insemination

  IVF

1276 (66.42)

240 (66.67)

1063 (67.15)

0.901

  ICSI

645 (33.58)

120 (33.33)

520 (32.85)

 

 Number of oocytes retrieved

   ≤ 10

712 (37.06)

123 (34.17)

535 (33.80)

0.171

  11–20

873 (45.45)

161 (44.72)

739 (46.68)

 

   > 20

336 (17.49)

76 (21.11)

309 (19.52)

 

Characteristics of FET cycle

 Day of embryo transfer

  Day3

1049 (73.35)

258 (71.67)

1140 (72.02)

0.724

  Day4

299 (15.56)

56 (15.56)

267 (16.87)

 

  Day5

213 (11.09)

46 (12.78)

176 (11.12)

 

 Number of embryo transferred

  Single embryo transfer

214 (11.14)

33 (9.17)

181 (11.43)

0.811

  Multiple embryo transfer

1707 (88.86)

327 (90.83)

1402 (88.57)

 

 Hormone level before embryo transfer

  E2, Median [IQR], ×103 pmol/L

1.20 [0.86–1.88]

1.64 [1.01–2.69]

1.86 [1.07–3.22]

< 0.001

  P4, Median [IQR], nmol/L

2.90 [1.80–3.60]

2.50 [1.50–2.60]

1.50 [0.90–2.40]

< 0.001

  LH, Median [IQR], IU/L

14.05 [9.20–24.90]

10.60 [6.90–17.40]

12.00 [7.50–20.30]

< 0.001

 Endometrial thickness, Mean ± SD, mm

9.54 ± 1.46

9.52 ± 1.52

9.55 ± 1.43

0.952

  1. FET frozen embryo transfer, NC natural cycles, OS ovarian stimulation, HRT hormonal replacement therapy, COH controlled ovarian stimulation, IVF in vitro fertilization, ICSI intracytoplasmic sperm injection, E2 estradiol, P4 progesterone, LH luteinizing hormone