Table 1 The top 20 up-regulated and down-regulated circRNAs between PE patients and controls
circRNA _ID | Chr | Length | Host gene | Normalized signal (log2) | Fold change | P | Regulation | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
PE- sample1 | PE- sample2 | PE- sample3 | NC- sample1 | NC- sample2 | NC- sample3 | |||||||
circ_0077259 | 6 | 336 | CGA | 5.14 | 5.06 | 5.15 | 0.90 | 2.56 | 0.88 | 10.83 | 2.20E-02 | up |
circ_0077260 | 6 | 521 | CGA | 3.93 | 3.91 | 4.54 | 1.36 | 0.91 | 0.89 | 8.50 | 4.22E-04 | up |
circ_0081930 | 7 | 164 | LAMB1 | 4.64 | 4.74 | 4.37 | 2.36 | 0.89 | 1.65 | 7.14 | 1.52E-02 | up |
circ_0043597 | 17 | 669 | KRT19 | 3.88 | 4.24 | 4.08 | 1.64 | 1.17 | 1.09 | 6.76 | 4.90E-04 | up |
circ_0037771 | 16 | 166 | NAGPA | 3.63 | 3.36 | 3.87 | 0.73 | 0.77 | 1.11 | 6.74 | 1.72E-04 | up |
circ_0075840 | 6 | 995 | GPLD1 | 4.20 | 4.27 | 4.31 | 1.97 | 2.27 | 1.20 | 5.21 | 1.58E-02 | up |
circ_0042232 | 17 | 126 | MPRIP | 3.75 | 4.60 | 3.99 | 2.20 | 1.40 | 1.75 | 5.06 | 2.55E-03 | up |
circ_0090100 | X | 525 | SAT1 | 4.38 | 4.12 | 4.44 | 1.64 | 2.37 | 1.90 | 5.00 | 2.90E-03 | up |
circ_0013777 | 1 | 2640 | NOTCH2 | 3.70 | 3.51 | 3.68 | 1.90 | 0.88 | 0.91 | 4.98 | 1.64E-02 | up |
circ_0081910 | 7 | 2197 | LAMB1 | 4.51 | 4.59 | 4.89 | 2.45 | 2.60 | 2.27 | 4.68 | 1.38E-04 | up |
circ_0036082 | 15 | 4057 | PAQR5 | 1.56 | 0.93 | 0.74 | 3.84 | 4.06 | 4.67 | 8.66 | 8.98E-04 | down |
circ_0042333 | 17 | 416 | TOP3A | 0.70 | 0.71 | 0.72 | 3.24 | 3.27 | 4.26 | 7.79 | 1.33E-02 | down |
circ_0062444 | 22 | 4291 | PPM1F | 0.75 | 0.76 | 0.75 | 3.66 | 2.88 | 3.94 | 6.99 | 1.32E-02 | down |
circ_0079385 | 7 | 245 | ZDHHC4 | 2.13 | 1.06 | 1.52 | 4.02 | 3.79 | 4.66 | 5.93 | 3.42E-03 | down |
circ_0076206 | 6 | 1290 | MTCH1 | 0.71 | 1.26 | 1.43 | 3.16 | 3.27 | 4.02 | 5.19 | 2.88E-03 | down |
circ_0066266 | 3 | 314 | FAM116A | 0.97 | 0.94 | 0.93 | 3.26 | 3.25 | 3.38 | 5.10 | 1.12E-04 | down |
circ_0004552 | 19 | 338 | CARM1 | 2.55 | 0.90 | 1.42 | 3.61 | 3.94 | 4.66 | 5.06 | 1.89E-02 | down |
circ_0011389 | 1 | 1136 | EIF3I | 0.87 | 0.74 | 1.78 | 3.78 | 3.24 | 3.22 | 4.69 | 7.77E-03 | down |
circ_0008808 | 15 | 772 | ARIH1 | 0.92 | 0.92 | 2.46 | 3.64 | 3.56 | 3.99 | 4.33 | 3.92E-02 | down |
circ_0029899 | 13 | 414 | USPL1 | 1.06 | 1.29 | 0.98 | 3.39 | 3.06 | 3.20 | 4.31 | 9.83E-05 | down |
circ_0077259 | 6 | 336 | CGA | 5.14 | 5.06 | 5.15 | 0.90 | 2.56 | 0.88 | 10.83 | 2.20E-02 | up |
circ_0077260 | 6 | 521 | CGA | 3.93 | 3.91 | 4.54 | 1.36 | 0.91 | 0.89 | 8.50 | 4.22E-04 | up |
circ_0081930 | 7 | 164 | LAMB1 | 4.64 | 4.74 | 4.37 | 2.36 | 0.89 | 1.65 | 7.14 | 1.52E-02 | up |
circ_0043597 | 17 | 669 | KRT19 | 3.88 | 4.24 | 4.08 | 1.64 | 1.17 | 1.09 | 6.76 | 4.90E-04 | up |
circ_0037771 | 16 | 166 | NAGPA | 3.63 | 3.36 | 3.87 | 0.73 | 0.77 | 1.11 | 6.74 | 1.72E-04 | up |
circ_0075840 | 6 | 995 | GPLD1 | 4.20 | 4.27 | 4.31 | 1.97 | 2.27 | 1.20 | 5.21 | 1.58E-02 | up |
circ_0042232 | 17 | 126 | MPRIP | 3.75 | 4.60 | 3.99 | 2.20 | 1.40 | 1.75 | 5.06 | 2.55E-03 | up |
circ_0090100 | X | 525 | SAT1 | 4.38 | 4.12 | 4.44 | 1.64 | 2.37 | 1.90 | 5.00 | 2.90E-03 | up |
circ_0013777 | 1 | 2640 | NOTCH2 | 3.70 | 3.51 | 3.68 | 1.90 | 0.88 | 0.91 | 4.98 | 1.64E-02 | up |
circ_0081910 | 7 | 2197 | LAMB1 | 4.51 | 4.59 | 4.89 | 2.45 | 2.60 | 2.27 | 4.68 | 1.38E-04 | up |
circ_0036082 | 15 | 4057 | PAQR5 | 1.56 | 0.93 | 0.74 | 3.84 | 4.06 | 4.67 | 8.66 | 8.98E-04 | down |
circ_0042333 | 17 | 416 | TOP3A | 0.70 | 0.71 | 0.72 | 3.24 | 3.27 | 4.26 | 7.79 | 1.33E-02 | down |
circ_0062444 | 22 | 4291 | PPM1F | 0.75 | 0.76 | 0.75 | 3.66 | 2.88 | 3.94 | 6.99 | 1.32E-02 | down |
circ_0079385 | 7 | 245 | ZDHHC4 | 2.13 | 1.06 | 1.52 | 4.02 | 3.79 | 4.66 | 5.93 | 3.42E-03 | down |
circ_0076206 | 6 | 1290 | MTCH1 | 0.71 | 1.26 | 1.43 | 3.16 | 3.27 | 4.02 | 5.19 | 2.88E-03 | down |
circ_0066266 | 3 | 314 | FAM116A | 0.97 | 0.94 | 0.93 | 3.26 | 3.25 | 3.38 | 5.10 | 1.12E-04 | down |
circ_0004552 | 19 | 338 | CARM1 | 2.55 | 0.90 | 1.42 | 3.61 | 3.94 | 4.66 | 5.06 | 1.89E-02 | down |
circ_0011389 | 1 | 1136 | EIF3I | 0.87 | 0.74 | 1.78 | 3.78 | 3.24 | 3.22 | 4.69 | 7.77E-03 | down |
circ_0008808 | 15 | 772 | ARIH1 | 0.92 | 0.92 | 2.46 | 3.64 | 3.56 | 3.99 | 4.33 | 3.92E-02 | down |
circ_0029899 | 13 | 414 | USPL1 | 1.06 | 1.29 | 0.98 | 3.39 | 3.06 | 3.20 | 4.31 | 9.83E-05 | down |