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Table 6 Sensitivity analyses

From: Maternal overweight but not paternal overweight before pregnancy is associated with shorter newborn telomere length: evidence from Guangxi Zhuang birth cohort in China

 

N

Percentage change (95% CI)

P-value

Maternal BMI

 Model B

  NW

753

Ref

 

  UW

255

0.23(−4.28,4.95)

0.929

  OW

74

−7.96(− 14.69, − 0.69)

0.032

 Excluding drinking before pregnancy

  NW

733

Ref

  UW

248

0.93(− 3.62,5.68)

0.678

  OW

74

−7.74(−14.49, − 0.69)

0.034

 Excluding passive smoking during pregnancy

  NW

294

Ref

  UW

97

−3.84(− 10.67,3.28)

0.285

  OW

30

−14.30(− 23.62, − 3.62)

0.010

 Excluding pregnancy comorbidities or complications

  NW

659

Ref

  UW

231

0.00(−4.72,4.71)

0.966

  OW

60

−10.05(−17.21, −2.28)

0.013

 Excluding preterm birth and low birth weight

  NW

709

Ref

  UW

231

0.46(−4.06,5.20)

0.836

  OW

72

−7.96(−14.69, −0.69)

0.033

 Excluding women from urban areas

  NW

704

Ref

 

  UW

241

0.69(−3.84,5.44)

0.793

  OW

68

−10.05(−16.82, −2.95)

0.007

Paternal BMI

 Model B

  HW

995

Ref

  OW

87

0.93(−5.59,8.14)

0.772

 Excluding drinking before pregnancy

  HW

972

Ref

  OW

83

−0.23(−6.89,6.91)

0.960

 Excluding passive smoking during pregnancy

  HW

396

Ref

  OW

25

−4.50(−15.67,8.14)

0.474

 Excluding pregnancy comorbidities or complications

  HW

875

Ref

  OW

75

0.93(−6.24,8.64)

0.793

 Excluding preterm birth and low birth weight

  HW

930

Ref

  OW

82

1.39(−5.38,8.89)

0.683

 Excluding women from urban areas

  HW

932

Ref

 

  OW

81

2.57(−4.28,9.90)

0.479

Parents’ weight status combination*

 Model B

  Both parents HW

928

Ref

  OW father, HW mother

80

0.69(−6.24,8.14)

0.866

  OW mother, HW father

67

−8.38(−15.47, −0.92)

0.028

 Excluding drinking before pregnancy

  Both parents HW

905

Ref

  OW father, HW mother

76

−0.69(−7.53,6.91)

0.860

  OW mother, HW father

67

−8.59(−15.47, −1.14)

0.026

 Excluding passive smoking during pregnancy

  Both parents HW

368

Ref

  OW father, HW mother

23

−3.62(−15.28,9.65)

0.582

  OW mother, HW father

28

−13.30(−23.09, −2.28)

0.021

 Excluding pregnancy comorbidities or complications

  Both parents HW

820

Ref

  OW father, HW mother

70

1.16(−6.24,9.14)

0.784

  OW mother, HW father

55

−10.05(−17.40, − 1.83)

0.018

 Excluding preterm birth and low birth weight

  Both parents HW

865

Ref

  OW father, HW mother

75

1.16(−6.03,8.64)

0.774

  OW mother, HW father

65

−8.59(−15.67, −0.92)

0.027

 Excluding women from urban areas

  Both parents HW

871

Ref

 

  OW father, HW mother

74

2.09(−4.94,9.65)

0.575

  OW mother, HW father

61

−10.87(−17.78, −3.39)

0.005

  1. Abbreviation: BMI Body mass index, TL Telomere length, UW Underweight, NW Normal weight, HW Healthy weight (normal and underweight), OW Overweight
  2. Models’ adjustments were according to model B in Table 2
  3. Preterm birth was defined as a newborn with gestational age < 37 weeks, low birth weight was defined as a newborn with birth weight < 2500 g
  4. *Both parents OW was excluded for a small number 7(0.6%)
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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