Maternal overweight but not paternal overweight before pregnancy is associated with shorter newborn telomere length: evidence from Guangxi Zhuang birth cohort in China

Table 5 Associations between parental pre-pregnancy BMI and newborn TL, stratified by maternal age at delivery

Subgroup	Maternal age at delivery (years)
	< 28(n = 978)		≥ 28(n = 104)
	Percentage change (95% CI)	P-value	Percentage change (95% CI)	P-value
Maternal pre-pregnancy BMI
NW	Ref		Ref
UW	−1.37(− 7.10,4.71)	0.647	1.16(− 5.59,8.39)	0.725
OW	−3.17(− 20.93,18.58)	0.756	− 8.38(− 15.67, − 0.46)	0.038
Paternal pre-pregnancy BMI
HW	Ref		Ref
OW	−1.37(− 11.08,9.40)	0.798	3.75(− 5.38,13.76)	0.434
Parents’ weight status combination*
Both parents HW	Ref		Ref
OW father, HW mother	−0.23(− 10.46,11.17)	0.966	2.09(− 7.10,12.20)	0.675
OW mother, HW father	2.33(−21.84,33.97)	0.866	−9.22(−16.63, − 1.37)	0.023

Abbreviation: BMI Body mass index, TL Telomere length, UW Underweight, NW Normal weight, HW Normal and underweight, OW Overweight
Models’ adjustments were according to model B in Table 2
*Both parents OW was excluded for a small number 7(0.6%)

ISSN: 1471-2393