Biomarkers for a histological chorioamnionitis diagnosis in pregnant women with or without group B streptococcus infection: a case-control study

Table 2 Characteristics of the included pregnant women grouped according to HCA

	HCA	Non-HCA	p value
No.	19	352
Age	28.63 (2.54)	29.52 (3.55)	0.282
Median (Min-Max)	29 (24–36)	29 (21–40)
Parity
1	17	239
2	2	101
3	–	12	0.135
GBS infection	8	51	0.001
Pathologic jaundice	5	27	0.005
Non-reassuring fetal status	5	39	0.045
Birth asphyxia	2	24	0.537
Low birth weight infant	4	9	< 0.001
Postpartum hemorrhage	3	13	0.011
Premature rupture of membrane	5	22	0.001
Preterm birth	2	24	0.537
Puerperal infection	10	15	< 0.001
SICAM-1(ng/L)	319.8 (296.3–376.4)	295.25 (283.3–307.15)	0.001
IL-8(ng/L)	1534.7 (1345.2–3528.1)	1120.6 (1025.1–1302.1)	< 0.001
TNF-α (ng/L)	37.1 (36.4–48.1)	30.1 (28.9–31.4)	< 0.001
WBC(×10⁹)	13.54 (7.37–15.38)	8.665 (7.475–10.895)	0.008
Neutrophil ratio (%)	84 (76–89)	77 (73–80.5)	< 0.001
CRP (mg/L)	12.3 (3.06–32.85)	3.2 (2.39–5.05)	0.002

Abbreviations: CRP C-reation protein, GBS Group B Streptococcus, HCA Histological chorioamnionitis, IL-8 Interleukin 8, sICAM-1 soluble Intercellular adhesion molecule-1, TNF-α Tumor necrosis factor α, WBC White blood cells

ISSN: 1471-2393