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Table 4 Outcome of ovary stimulation and embryo culture by AMH percentile according to age

From: Age-specific definition of low anti-Mullerian hormone and associated pregnancy outcome in women undergoing IVF treatment

 

Age of patients < 35

P value

Retrieval cycles with AMH > 10th centile (n = 614)

Retrieval cycles with AMH ≤ 10th centile (n = 84)

Days of ovarian stimulation

11 ± 2.5

7.2 ± 5.1

< 0.01

Total gonadotropin dose (IU)

2850 ± 1302

1853 ± 1525

< 0.01

Estradiol level on trigger day (pg/ml)

3187 ± 1454

980 ± 882

< 0.01

Endometrial thickness on trigger day (mm)

10.2 ± 2.7

7.6 ± 2.9

< 0.01

Total number of oocytes retrieved

12.3 ± 6.5

2.7 ± 4.0

< 0.01

Number of MII oocytes retrieved

10.9 ± 6.2

2.4 ± 3.3

< 0.01

Total number of embryo available for transfer

4.3 ± 2.8

1.0 ± 1.2

< 0.01

Number of D5 or D6 blastocyst available for transfer

1.5 ± 1.9

0.1 ± 0.4

< 0.01

 

Age of patients ≥35

 

Retrieval cycles with AMH > 10th centile (n = 520)

Retrieval cycles with AMH ≤ 10th centile (n = 63)

Days of ovarian stimulation

9.1 ± 4.2

5.5 ± 5.2

< 0.01

Total gonadotropin dose (IU)

2500 ± 1420

1728 ± 1677

< 0.01

Estradiol level on trigger day (pg/ml)

2061 ± 1503

740 ± 735

< 0.01

Endometrial thickness on trigger day (mm)

8.5 ± 3.1

7.3 ± 2.7

< 0.01

Total number of oocytes retrieved

6.4 ± 5.9

1.5 ± 2.1

< 0.01

Number of mature oocytes retrieved

5.7 ± 5.4

1.3 ± 2.0

< 0.01

Total number of embryo available for transfer

2.4 ± 2.2

0.6 ± 0.8

< 0.01

Number of D5 or D6 blastocyst available for transfer

0.6 ± 1.2

0.1 ± 0.3

< 0.01