Table 2 Association of thyroid antibodies with maternal outcomes in hypothyroid pregnancies
Maternal Outcomes | Anti-TPO | P value | Odds ratio | 95% CI | Anti-TG | P value | Odds ratio | 95% CI | ||
|---|---|---|---|---|---|---|---|---|---|---|
Positive N (%) N = 97 | Negative N (%) N = 49 | Positive N (%) N = 76 | Negative N (%) N = 70 | |||||||
Abortions | ||||||||||
 Yes | 8 (8.2%) | 4 (8.2%) | 1.000 | 1.011 | 0.289- | 6 (7.9%) | 6 (8.6%) | 0.915 | 1.059 | 0.371- |
 No | 89 (91.8%) | 45 (91.8%) |  |  | 3.539 | 70 (92.1%) | 64 (91.4%) |  |  | 3.026 |
Gestational hypertension | ||||||||||
 Yes | 7 (4.9%) | 13 (16.0%) | 0.005 | 0.267 | 0.102- | 5 (4.3%) | 15 (13.9%) | 0.011 | 0.277 | 0.097- |
 No | 137 (95.1%) | 68 (84.0%) |  |  | 0.701 | 112 (95.7%) | 93 (86.1%) |  |  | 0.790 |
Pre-eclampsia | ||||||||||
 Yes | 8 (5.6%) | 4 (4.9%) | 1.000a | 1.132 | 0.330–3.883 | 7 (6.0%) | 5 (4.6%) | 0.652 | 1.311 | 0.403–4.261 |
 No | 136 (94.4%) | 77 (95.1%) |  |  |  | 110 (94.0%) | 103 (95.4%) |  |  |  |
Postpartum Hemorrhage | ||||||||||
 Yes | 51 (35.4%) | 37 (45.7%) | 0.130 | 0.652 | 0.374–1.136 | 43 (36.8%) | 45 (41.7%) | 0.450 | 0.814 | 0.476- |
 No | 93 (64.6%) | 44 (54.3%) |  |  |  | 74 (63.2%) | 63 (58.3%) |  |  | 1.391 |
Mode of labor | ||||||||||
 Spontaneous | 29 (22.8%) | 10 (13.3%) | 0.207 | 1.923b | 0.878- | 17 (16.5%) | 22 (22.2%) | 0.136 | 0.692b | 0.342- |
 Induced | 27 (21.3%) | 24 (32.0%) |  |  | 4.213 | 24 (23.3%) | 27 (27.3%) |  |  | 1.398 |
 Augmented | 20 (15.7%) | 10 (13.3%) |  |  |  | 21 (20.4%) | 9 (9.1%) |  |  |  |
 Not applicable due to CS | 51 (40.2%) | 31 (41.3%) |  |  |  | 41 (39.8%) | 41 (41.4%) |  |  |  |
Mode of delivery | ||||||||||
 Em-LSCS | 28 (22.0%) | 24 (32.0%) | 0.649 | 0.838b | 0.465- | (18.4%) | 33 (33.3%) | 0.072 | 0.763b | 0.432- |
 LSCS | 48 (37.8%) | 24 (32.0%) |  |  | 1.512 | 41 (39.8%) | 31 (31.3%) |  |  | 1.347 |
 Instrumental | 6 (4.7%) | 3 (4.0%) |  |  |  | 6 (5.8%) | 3 (3.0%) |  |  |  |
 SVD | 17 (13.4%) | 9 (12.0%) |  |  |  | 11 (10.7%) | 15 (15.2%) |  |  |  |
 SVD with episiotomy | 28 (22.0%) | 15 (20.0%) |  |  |  | 26 (25.2%) | 17 (17.2%) |  |  |  |