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Table 2 Association of thyroid antibodies with maternal outcomes in hypothyroid pregnancies

From: Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4)

Maternal Outcomes Anti-TPO P value Odds ratio 95% CI Anti-TG P value Odds ratio 95% CI
Positive
N (%)
N = 97
Negative
N (%)
N = 49
Positive
N (%)
N = 76
Negative
N (%)
N = 70
Abortions
 Yes 8 (8.2%) 4 (8.2%) 1.000 1.011 0.289- 6 (7.9%) 6 (8.6%) 0.915 1.059 0.371-
 No 89 (91.8%) 45 (91.8%)    3.539 70 (92.1%) 64 (91.4%)    3.026
Gestational hypertension
 Yes 7 (4.9%) 13 (16.0%) 0.005 0.267 0.102- 5 (4.3%) 15 (13.9%) 0.011 0.277 0.097-
 No 137 (95.1%) 68 (84.0%)    0.701 112 (95.7%) 93 (86.1%)    0.790
Pre-eclampsia
 Yes 8 (5.6%) 4 (4.9%) 1.000a 1.132 0.330–3.883 7 (6.0%) 5 (4.6%) 0.652 1.311 0.403–4.261
 No 136 (94.4%) 77 (95.1%)     110 (94.0%) 103 (95.4%)    
Postpartum Hemorrhage
 Yes 51 (35.4%) 37 (45.7%) 0.130 0.652 0.374–1.136 43 (36.8%) 45 (41.7%) 0.450 0.814 0.476-
 No 93 (64.6%) 44 (54.3%)     74 (63.2%) 63 (58.3%)    1.391
Mode of labor
 Spontaneous 29 (22.8%) 10 (13.3%) 0.207 1.923b 0.878- 17 (16.5%) 22 (22.2%) 0.136 0.692b 0.342-
 Induced 27 (21.3%) 24 (32.0%)    4.213 24 (23.3%) 27 (27.3%)    1.398
 Augmented 20 (15.7%) 10 (13.3%)     21 (20.4%) 9 (9.1%)    
 Not applicable due to CS 51 (40.2%) 31 (41.3%)     41 (39.8%) 41 (41.4%)    
Mode of delivery
 Em-LSCS 28 (22.0%) 24 (32.0%) 0.649 0.838b 0.465- (18.4%) 33 (33.3%) 0.072 0.763b 0.432-
 LSCS 48 (37.8%) 24 (32.0%)    1.512 41 (39.8%) 31 (31.3%)    1.347
 Instrumental 6 (4.7%) 3 (4.0%)     6 (5.8%) 3 (3.0%)    
 SVD 17 (13.4%) 9 (12.0%)     11 (10.7%) 15 (15.2%)    
 SVD with episiotomy 28 (22.0%) 15 (20.0%)     26 (25.2%) 17 (17.2%)    
  1. Em-LSCS emergency lower segment caesarean section, SVD spontaneous vaginal delivery. P-values calculated by Chi square test applied. aFischer test applied. P-value significant at <=0.05. bOdds ratio for spontaneous mode of labor and for C-section mode of delivery