Skip to main content

Table 1 Summary of all reported cases with haemostatic complications, coagulopathies or DIC in pregnant women with confirmed COVID-19 infection

From: Haemostatic and thrombo-embolic complications in pregnant women with COVID-19: a systematic review and critical analysis

Location

Source

(Study number as per ripe-tomato.org or database)

Pregnant women with confirmed COVID-19 infection with outcomes reported

Women who required critical care.

N/A not available

Women who delivered, presumed healthy1

Women with ongoing pregnancies, presumed healthy1

Venous thrombotic events

Arterial thrombotic events

Disseminated intravascular coagulation (DIC) events

China

 Zhongnan Hospital of Wuhan University

1

9

0

9

0

0

0

0

 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

2a

3

0

3

0

0

0

0

 The first Affiliated Hospital, College of Medicine, Zhejiang University

4

1

0

1

0

0

0

0

 Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

6

15

0

11

4

0

0

0

 Qingdao Women and Children’s Hospital, Qingdao

7

1

0

0

1

0

0

0

 Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

15

7

0

7

0

0

0

0

 Affiliated Infectious Hospital of Soochow University, Suzhou

19

1

1

1

0

0

0

0

 Maternal and Child Hospital of Hubei Province

30

34

0

34

0

0

0

0

 Beijing YouAn Hospital, Capital Medical University

34

1

0

1

0

0

0

0

 Renmin Hospital of Wuhan University

36

173a

N/A

14

0

0

0

0

 Renmin Hospital of Wuhan University

37

3

0

3

0

0

0

0

 No 2 People’s Hospital of Hefei City Affiliated to Anhui Medical University

62

1

0

1

0

0

0

0

 Central Hospital of Wuhan

73

284e

N/A

22

2

0

0

0

 Xiaolan People’s Hospital of Zhongshan, Guandong

81

1

1

1

0

0

0

1

USA

 MedStar Washington Hospital Center, DC

21

1

0

1

0

0

0

0

 Newark Beth Israel Medical Centre, New Jersey

28

2a,b

N/A

0

0

0

0

0

 Saint Barnabas Medical Center, Livingston, New Jersey

111

1

1

1

0

0

0

0

 Morristown medical centre, St Peter’s University Medical Centre, New Jersey

159

3

3

0

3

0*

0

0

 “Network’s 2 largest hospitals” in New Jersey: Likely Hackensack University Medical Centre, Rutgers New Jersey Medical School Newark, Seton Hall University Nutley, Jersey Shore University Medical Centre, Neptune,

149

8

8

7

1

0

0

0

 Good Samaritan Hospital, Cincinnati, Ohio

50

1b

1

0

0

0

0

0**

 Lexington Medical Centre, West Columbia, South Carolina

60

1

0

0

1

0

0

0

 Hospital of the University of Pennsylvania

65

5b

5

3

1

1

0

0

 Washington University in St Louis, Missouri

69

1

1

1

0

0

0

0

 Beaumont Hospital Dearborn, Dearborn, Michigan

123

16

0

10

6

0

0

0

 Henry Ford Hospital Department of Obstetrics and Gynecology, Detroit, Michigan (distinct case from 123)

87

1

1

0

1

0

0*

0

 University of California, San Francisco, California

89

1

1

1

0

0

0

0

 Stanford University Hospital, California

115

1

0

1

0

0

0

0

 New York University, Winthrop hospital, Langone health

91

1

1

1

0

0

0

0

 New York University, Langone Health (distinct case)

98

1c

0

0

0

0

0

0

 Weil Cornell Medicine, New York**

99

20h

0

19

0

0

0

0

 Norwell Group, New York

118

162

132g,a

13

5

5

0

0

0**

 New York University, Langone health

152

2

2

2

0

0

0

0

 Six hospital systems in Washington state

102

46

1

8

38

0

0

0

 University of Tennessee Health Science Center, Nashville, United States

112

1

1

0

1

0

0

0

 Yale School of Medicine

155

1e

N/A

0

0

0

0

1

 Advocate Good Samaritan Hospital, Illinois, United States^

COV-PREG-COAG

1

0

1

0

0

0

0

 St Joseph Hospital, Denver

156

1

0

1

0

0

0

0

Canada

 Mount Sinai Hospital, Toronto

48

1

0

1

0

0

0

1

Honduras

 Hospital Escuela de Tegucigalpa

18

1

0

1

0

0

0

0

Sweden

 Southern General Hospital, Stockholm

20

1

0

1

0

0

0

0

France

 Antoine Beclere Hospital, Clamart

48

1

N/A

1

0

0

0

1

 Hospitaux Universitaires de Strasbourg

161

54a,b,d

5

20

31

0

0

0

Canary Islands

 Hospitalario Universitario Insular Materno Infantil, Gran Canaria

53

1

1

1

0

0

0

0

Italy

 Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

76

7c

N/A

4

2

0

0

0

 12 Italian hospitals (non-overlapping with others in table)

117

26

14

6

20

0

0

0

 Parma Hospital, Italy

109

4

N/A

4

0

0

0

0

 6 hospitals of Azienda USL

62 “Toscana Nord Ovest” [ATNO] (Tuscany), and Gaslini Children’s Hospital (Genoa, Liguria)

133

3

0

3

0

0

0

0

UK

 Portland Hospital London

82

8

0

8

0

0

0

0

 East Midlands Research group (University Hospitals of Leicester and Nottingham University Hospitals)

East Midlands Research Group

30b,g

2

21

7

0

0

1

 UK (Nationwide)- UKOSS database with case information as per paper 107.

UKOSS + 107

4275g

41

261

161

1

1

0

Belgium

 Cliniques Universitaires, St Luc, Brussels,

100

1

0

1

0

0

0

0

 4 Obstetric units in North East Flanders

128

13

0

13

0

0

0

0

Portugal

 Hospital Pedro Hispano

105

12

0

10

2

0

0

0

 Porto (distinct case)

94

1

0

1

0

0

0

0

 Portugal (distinct case)

74

1

0

1

0

0

0

0

Netherlands

 Netherlands COVID-19 registry

141

176d,g,i

7

49

124

1g

0

0

Germany

 Ulm university

127

2

0

2

0

0

0

0

Spain

 Jaen

158

4

0

0

4

0

0

0

 Barcelona

140

8

8

4

4

0

0

0

South Korea

 Daegu Fatimal Hospital

22

1

0

1

0

0

0

0

Japan

 Keio University Hospital, Tokyo

144

2

0

0

2

0

0

0

Turkey

 Ankara University Faculty of Medicine,

31

1b

1

0

0

0

0

0

 Sehit Prof Dr. Ilhan Varank Sancaktepe Training and Research Hospital, Istanbul

146

8c

1

2

5

0

0

0

 Necmettin Erkbakan University, Konya

145

1

0

1

0

0

0

0

Jordan

 Jordan

153

1

0

1

0

0

0

0

Australia

 Gold Coast University Hospital

45

1

0

1

0

0

0

0

India

 Designated Covid Hospital

58

1

0

1

0

0

0

0

Iran

 Tehran/Rasht/Qom/Zanjan

67

97g,b

9

1

0

0

0

1**

 Imam Khomeini Hospital, Sari, Iran

70

1g

1

0

0

0

0

0

 Imam Reza Hospital of Tabriz, Iran

101

1b

1

0

0

0

0

1

Thailand

 Thailand (reported by ministry of public health)

110

1f

0

0

0

0

0

0

Russia

 Russian Federation, Private Center^

COV-PREG-COAG

1

0

1

0

0

0

0

UAE

 Al Ain Hospital, United Arab Emirates^

COV-PREG-COAG

1

0

1

0

0

0

0

 Location

 

Pregnant women with confirmed COVID-19 infection with outcomes reported

Women who required critical care.

N/A not available

Women who delivered, presumed healthy1

Women with ongoing pregnancies, presumed healthy1

Venous thrombotic events

Arterial thrombotic events

Disseminated intravascular coagulation (DIC) events

Total

 

1063

132/1033

593

426

3

1

7

  1. a-remains inpatient (6), b-remains inpatient- stated to be on ITU/ventilator (8), c-Pregnancy loss before 24 weeks (3), d-pregnancy loss (gestation not stated) (2), e-termination before 24 weeks (due to COVID-19) (5), f- termination before 24 weeks (other reason) (1), g-patient died (17), h-readmission with nil further details (1), i-molar pregnancy (1)
  2. *line thrombosis noted (see Table 2)
  3. **Additional coagulopathy noted (see Table 3)
  4. *** Isolated abnormal coagulation parameters- not specified further
  5. 1Few papers specifically stated negative findings for coagulopathy or thrombosis. Cases were therefore considered negative for these events if it was stated that there were no complications during the observed clinical course, or if patients were stated to have recovered/be recovering, or discharged without mention of coagulopathy or thrombosis