Mild thrombocytopenia indicating maternal organ damage in pre‐eclampsia: a cross‐sectional study

Table 1 The criteria of maternal organ damage and utero-placental dysfunction

λ Liver involvement without underlying diseaseAST or ALT > 40 IU/L with or without right upper quadrant or epigastric abdominal pain
λ Acute kidney injury Serum creatine level ≥ 90 umol/L; 1.0 mg/dL
λ Neurological complications Eclampsia, altered mental status, blindness, stroke, clonus, severe headache, or persistent visual scotoma
λ Blood coagulation disorders Thrombocytopenia: platelet count < 150 × 10⁹/L, disseminated intravascular coagulation, or hemolysis
λ Utero-placental dysfunction Fetal growth restriction^a, abnormal umbilical artery doppler waveform^b, or stillbirth^c

^a: Estimated fetal weight < − 1.5 standard deviation without chromosomal abnormality and multiple congenital anomaly syndrome
^b: Absent or reversal of end diastolic flow, or extremely high pulsatility index or resistance index
^c: The cases of stillbirth with chromosomal abnormality or multiple congenital anomaly syndrome are excluded
AST aspartate transaminase; ALT alanine transaminase

ISSN: 1471-2393