BMC Pregnancy and Childbirth

Table 6 Beta coefficients (95% CI) for maternal total, HDL and LDL cholesterol and triglycerides levels, at enrolment, 20 and 30 weeks gestation, in association with birth weight in grams

From: Maternal plasma lipid levels across pregnancy and the risks of small-for-gestational age and low birth weight: a cohort study from rural Gambia

Gestation week	Unadjusted			Adjusted^a
Gestation week	R²	β (95% CI)	*p-value*	R²	β (95% CI)	*p-value*
Total cholesterol
Enrolment^b	0.012	0.90 (−0.01, 1.9)	0.052	0.152	1.1 (− 0.01, 2.2)	0.053
20 weeks	0.010	1.3 (0.20, 2.4)	0.026	0.130	1.3 (0.20, 2.5)	0.027
30 weeks	0.012	1.1 (0.30, 1.9)	0.006	0.098	1.2 (0.30, 2.0)	0.006
HDL cholesterol
Enrolment^b	0.002	0.10 (−2.2, 2.4)	0.933	0.140	0.66 (−2.0, 3.3)	0.621
20 weeks	0.001	1.0 (−1.5, 3.6)	0.427	0.113	1.5 (−1.3, 4.2)	0.295
30 weeks	0.001	0.80 (− 1.5, 3.0)	0.500	0.086	0.90 (−1.5, 3.3)	0.457
LDL cholesterol
Enrolment^b	0.009	1.0 (−0.10, 2.2)	0.080	0.142	0.80 (− 0.40, 2.1)	0.206
20 weeks	0.009	1.3 (0.10, 2.5)	0.033	0.119	1.1 (−0.10, 2.4)	0.082
30 weeks	0.018	1.5 (0.60, 2.4)	0.001	0.104	1.5 (0.50, 2.4)	0.002
Triglycerides
Enrolment^b	0.003	0.40 (−1.1, 2.0)	0.589	0.139	0.80 (− 1.0, 2.7)	0.385
20 weeks	0.002	0.70 (−0.60, 2.1)	0.292	0.119	0.50 (−1.0, 2.0)	0.511
30 weeks	0.007	1.1 (0.10, 2.1)	0.039	0.093	1.0 (−0.10, 2.1)	0.068

^aLinear regression models were adjusted with maternal age, parity, gestational age, hemoglobin concentration, BMI, supplement group, and compliance to supplement during pregnancy, and infant birth sex and birth season
^bMean (SD) gestational age at enrolment was 13.9 (3.3) weeks gestation
Abbreviations: HDL high-density lipoprotein, LDL low-density lipoprotein

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