Table 2 Diagnostic models of early diagnosis for AFLP
From: Early diagnostic test for acute fatty liver of pregnancy: a retrospective case control study
Diagnostic model | Sensitivity (%) (95%CI) | Specificity(%) (95%CI) | NPV (%) (95%CI) | PPV (%) (95%CI) |
|---|---|---|---|---|
Gastrointestinal symptoms + AT +bile acid +APTT/PT | 97.6 (87.1–100) | 96.5 (92.6–98.7) | 99.4 (96.7–100) | 87.0 (73.7–95.1) |
Gastrointestinal symptoms + AT + bile acid + APTT/PT + bilirubin | 97.6 (87.1–100) | 97.1 (93.3–99.0) | 99.4 (96.7–100) | 88.9 (75.9–96.3) |
Gastrointestinal symptoms +blood pressure + AT +bile acid + APTT/PT+ bilirubin | 78.1 (62.4–89.4) | 97.7 (94.1–99.4) | 94.9 (90.6–97.6) | 88.9 (73.9–96.9) |
Gastrointestinal symptoms + AT +bile acid + APTT/PT + bilirubin + blood sugar | 12.2 (4.1–26.2) | 98.8 (95.8–100) | 82.5 (76.6–87.4) | 71.4 (29.0–96.3) |
Gastrointestinal symptoms + AT +bile acid+ APTT/PT + bilirubin + white blood cells | 92.7 (80.1–98.5) | 98.3 (95.0–99.6) | 98.3 (95.0–99.6) | 92.7 (80.1–98.5) |
Gastrointestinal symptoms + AT +bile acid+ APTT/PT + bilirubin + white blood cells +blood sugar | 12.2 (4.1–26.2) | 99.4 (96.8–100) | 82.6 (76.7–87.5) | 83.3 (35.8–99.6) |