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Table 3 Relationship between ACS with weight changes during hospitalization in VLBW preterm infants

From: Single-course antenatal corticosteroids is related to faster growth in very-low-birth-weight infant

Variable

Unadjusted coefficient

Adjusted coefficient a

Total

Postnatal age, week

45.52(40.91,50.12) *

74.23(56.03,92.42) *

Non-ACS

0.00(Reference)

0.00(Reference)

Single-course

23.54(−9.32,56.39)

1.54(− 29.76,32.84)

Repeated course

− 19.29(− 48.41,9.82)

− 12.61(− 40.30,15.06)

Time* single-course

18.24(10.07,26.42) *

14.75(6.02,23.49) *

Time* repeated course

10.12(2.94,17.31) *

5.48(−2.24,13.21)

Repeated course

0.00(Reference)

0.00(Reference)

Single-course

42.83(5.94,79.71) *

14.15(−20.38,48.70)

Time* single-course

8.12(−1.02,17.26)

9.27(−0.41,18.96)

GA < 28 weeks

Postnatal age, week

34.10(19.85,48.35) *

53.59(−21.00,128.20)

Non-ACS

0.00(Reference)

0.00(Reference)

Single-course

−81.72(−201.53,38.09)

−83.94(− 211.27,43.38)

Repeated course

−38.34(−138.91,62.23)

3.73(−98.58,106.05)

Time* single-course

22.00(−6.99,50.98)

20.31(−13.07,53.70)

Time* repeated course

4.21(−19.85,28.27)

4.68(−21.17,30.54)

Repeated course

0.00(Reference)

0.00(Reference)

Single-course

−43.38(−179.30,92.55)

−87.68(− 232.75,57.38)

Time* single-course

17.79(−15.27,50.85)

15.63(−21.84,53.10)

28 weeks ≤ GA < 32 weeks

Postnatal age, week

43.27(37.93,48.61) *

73.43(51.71,95.15) *

Non-ACS

0.00(Reference)

0.00(Reference)

Single-course

31.99(−4.93,68.90)

10.90(−25.09,46.90)

Repeated course

−14.48(−46.59,17.63)

−14.67(−46.41,17.06)

Time* single-course

19.99(10.51,29.46) *

15.71(5.54,25.88) *

Time* repeated course

10.55(2.36,18.73) *

5.26(−3.66,14.20)

Repeated course

0.00(Reference)

0.00(Reference)

Single-course

46.47(5.51,87.42) *

25.57(−14.02,65.17)

Time* single-course

9.43(−1.05,19.92)

10.44(−0.81,21.69)

32 weeks ≤ GA < 37 weeksb

  1. Point estimates and 95% CI of differences in mean weight or weight growth rate are shown
  2. VLBW very-low-birth-weight, ACS Antenatal corticosteroids, GA gestational age
  3. *Significantly different from reference group
  4. a Adjusted for sex, feeding pattern, cesarean section rate, time to start enteral nutrition, 5 min APGAR score, GA, multiple birth, amino acid and lipid introduction, duration of amino acid and lipid
  5. b Iteration is terminated but convergence has not been achieved. Validity of the model fit is uncertain
  6. All data were collected until 37 postconceptional age or at discharge