|
SNP ID
|
Model (n)
|
BMI
|
TC
|
TG
|
HDL
|
LDL
|
TG/HDL
|
TSH
|
T3
|
T4
|
|---|
|
rs2232365(C/T)
|
TT + CT(82)
|
29.01(26.63–34.05)
|
5.80(5.06–7.06)
|
3.72(2.81–4.66)
|
1.61(1.33–1.95)
|
2.91(2.36–3.72)
|
2.35(1.64–3.23)
|
3.29(2.31–5.42)
|
4.05(3.49–4.48)
|
12.14(10.59–14.24)
|
| |
CC(25)
|
29.88(28.26–31.96)
|
6.21(5.22–6.75)
|
3.30(2.89–3.99)
|
1.77(1.63–2.10)
|
2.97(2.46–3.58)
|
1.88(1.52–2.32)
|
4.44(3.18–5.19)
|
3.93(3.45–4.58)
|
12.00(10.74–12.64)
|
| |
P
|
0.219
|
0.688
|
0.118
|
0.040*
|
0.874
|
0.016*
|
0.475
|
0.953
|
0.371
|
|
rs3853839(C/G)
|
CC + CG(44)
|
30.17(26.83–34.18)
|
5.64(4.67–6.47)
|
3.51(2.84–4.50)
|
1.55(1.30–1.86)
|
2.77(2.38–3.44)
|
2.32(1.84–2.88)
|
3.84(2.06–5.75)
|
4.38(3.86–4.98)
|
12.08(10.33–13.27)
|
| |
GG(63)
|
29.00(26.91–32.43)
|
6.21(5.22–7.06)
|
3.60(2.84–4.59)
|
1.74(1.49–2.07)
|
3.02(2.45–3.93)
|
2.09(1.48–3.03)
|
3.68(2.62–5.31)
|
3.87(3.35–4.38)
|
12.00(10.90-13.64)
|
| |
P
|
0.296
|
0.141
|
0.648
|
0.063
|
0.222
|
0.425
|
0.894
|
0.005*
|
0.423
|
|
rs3761548(T/G)
|
GG + TG(102)
|
29.10(26.76–32.77)
|
5.96(5.06–7.02)
|
3.57(2.81–4.51)
|
1.67(1.38–1.97)
|
2.95(2.39–3.77)
|
2.18(1.53–2.92)
|
3.70(2.39–5.43)
|
4.02(3.45–4.52)
|
12.08(10.58–13.54)
|
| |
TT(5)
|
34.29(29.24–35.20)
|
6.57(5.46–6.75)
|
3.60(3.35–4.96)
|
1.78(1.62–2.13)
|
2.77(2.70–3.10)
|
2.72(1.94–2.79)
|
3.65(1.96–4.74)
|
3.98(3.87–4.58)
|
12.00(11.86–12.02)
|
| |
P
|
0.083
|
0.831
|
0.456
|
0.560
|
0.745
|
0.626
|
0.658
|
0.935
|
0.859
|
- LOPE represents late-onset preeclampsia, BMI Body mass index, TSH Thyroid-stimulating hormone, FT3 Free triiodothyronine, FT4 Free thyroxine, TC Total cholesterol, TG Triglyceride, HDL-C High-density lipoprotein, LDL-C Low-density lipoprotein, TG/HDL Triglyceride/ high-density lipoprotein. *P < 0.05 versus controls
