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Table 6 Predicted value and diagnostic value of prenatal screening for Trisomy 21 (%)

From: New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age

Group Screening for disease Sensitivity Specificity Positive predictive value Negative predictive value False positive rate False negative rate
AMA Trisomy 21 71.43 80.56 0.80 99.92 19.43 28.57
Non-AMA Trisomy 21 50.00 94.92 0.24 99.99 5.08 50.00