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Table 6 Predicted value and diagnostic value of prenatal screening for Trisomy 21 (%)

From: New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age

Group

Screening for disease

Sensitivity

Specificity

Positive predictive value

Negative predictive value

False positive rate

False negative rate

AMA

Trisomy 21

71.43

80.56

0.80

99.92

19.43

28.57

Non-AMA

Trisomy 21

50.00

94.92

0.24

99.99

5.08

50.00