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Table 3 Growth in early pregnancy and risk of preterm birth, very preterm and moderate preterm birth. (N = 2838 births)

From: Accelerated fetal growth in early pregnancy and risk of preterm birth: a prospective cohort study

Growth at second trim scan All preterm births
(n = 2838)
Very preterm births
(n = 378)
Moderate preterm births
(n = 2460)
No. of women Odds ratio (95% CI) No. of women Odds ratio (95% CI) No. of women Odds ratio (95% CI)
Crude Adjustedd Crude Adjustedd Crude Adjustedd
Accelerated fetal growtha 389 1.39 (1.25–1.56)* 1.36 (1.20–1.54)* 52 1.38 (1.01–1.86)** 1.33 (0.96–1.83)** 337 1.39 (1.24–1.57)* 1.36 (1.18–1.55)*
Appropriate fetal growthb 2215 Ref Ref 295 Ref Ref 1920 Ref Ref
Delayed fetal growthc 234 0.85 (0.73–0.96)* 0.84 (0.71–0.97)* 31 0.84 (0.58–1.21)*** 0.73 (0.47–1.12)*** 203 0.84 (0.72–0.97)* 0.85 (0.73–1.00)*
  1. aAccelerated fetal growth at second trimester scan was defined as BPD measurement at the 90th percentile, or more of the expected for gestational age
  2. bAppropriate fetal growth at second trimester scan was defined as BPD measurement between 10th -90th percentile of the expected for gestational age
  3. cDelayed fetal growth at second trimester scan was defined as BPD measurement at the 10th percentile, or less of the expected for gestational age
  4. dAdjusted OR for maternal age older than 35 yrs., short maternal height < 155 cm, BMI ≥ 30 kg/m2, non-Nordic origin, primiparity, smoking, IVF, pre-gestational diabetes mellitus, chronic hypertension and male fetal gender
  5. *p < 0.0001
  6. **p < 0.05
  7. ***p > 0.05