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Table 2 Odds ratios of male hypospadias

From: Association of abnormal placental perfusion with the risk of male hypospadias: a hospital-based retrospective cohort study

Characteristics

Male hypospadias

Crude odds ratio (95% CI)

Adjusted odds ratio (95% CI)

Placental perfusion

 Normal

1.00

1.00

 Abnormal a

2.87 (1.33–6.18)

2.40 (1.09–5.29)

 NA

1.10 (0.52–2.29)

1.12 (0.53–2.37)

Preeclampsia

 No

1.00

1.00

 Yes

Mild

1.76 (0.54–5.73)

1.56 (0.47–5.11)

Severe

10.81 (3.82–30.66)

7.75 (2.62–22.89)

Maternal age at delivery (years)

 ≥ 35

1.00

1.00

 25–34

0.89 (0.35–2.27)

0.74 (0.27–1.99)

 < 25

–

–

Residence

 Shanghai

1.00

1.00

 Other provinces

0.78 (0.36–1.67)

0.90 (0.41–1.96)

Parity

 Nulliparous

1.00

1.00

 Multiparous

0.41 (0.13–1.31)

0.39 (0.11–1.33)

Gestational diabetes mellitus

 No

1.00

1.00

 Yes

0.80 (0.25–2.60)

0.68 (0.21–2.23)

Assisted conception

 No

1.00

1.00

 Yes

2.66 (0.64–11.02)

1.96 (0.45–8.55)

  1. NA Not applicable
  2. a Abnormal placental perfusion was defined as any one abnormality of the six markers, which otherwise were normal