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Table 2 The clinical outcomes of patients in groups A–E stratified by 35 years of age

From: Live birth rate and neonatal outcomes of different quantities and qualities of frozen transferred blastocyst in patients requiring whole embryo freezing stratified by age

  <35 years of age ≥ 35 years of age
Group A Group B Group C Group D Group E P # Group A Group B Group C Group D Group E P #
Cycles (n) 1425 844 206 183 120   144 269 107 39 25  
Implantation rate 63.72b,c(908/1425) 60.37(1019/1688) 53.64(221/412) 45.90(168/366) 46.67(56/120) 0.000 55.56b,c(80/144) 52.97(285/538) 40.19(86/214) 26.92(21/78) 40.0(10/25) 0.000
Pregnancy rate 63.72a,b(908/1425) 75.59(638/844) 72.33(149/206) 62.30(114/183) 46.67d(56/120) 0.000 55.56a(80/144) 73.23(197/269) 57.0(61/107) 41.03(16/39) 40.0(10/25) 0.000
Live birth 54.25a,b(773/1425) 64.57
(545/844)
64.08
(132/206)
48.63
(89/183)
36.67 d(44/120) 0.000 42.36a(61/144) 59.48(160/269) 48.60(52/107) 30.77(12/39) 24.0(6/25) 0.000
Singleton 52.70a,b,c
(751/1425)
33.05(279/844) 38.84(80/206) 25.13(46/183) 36.67d
(44/120)
0.000 40.97
(59/144)
38.29(103/269) 33.64(36/107) 23.08(9/39) 24.0
(6/25)
0.177
Twin 1.55a,b,c
(22/1425)
31.52(266/844) 25.24(52/206) 23.50
(43/183)
0.0d
(0/120)
0.000 1.39a,b
(2/144)
21.19
(57/269)
14.95
(16/107)
7.69
(3/39)
0.0
(0/25)
0.000
Multiple pregnancy rate 3.52a,b,c
(32/908)
62.38
(398/638)
49.66
(74/149)
50.0
(57/114)
0.0d
(0/56)
0.000 6.25a,b,c
(5/80)
49.24
(97/197)
42.62
(26/61)
31.25
(5/16)
10.0
(1/10)
0.000
Monozygotic twins rate 3.52
(32/908)
2.66
(17/638)
1.34
(2/149)
2.63
(3/114)
0.0
(0/56)
0.462 6.25
(5/80)
4.57
(9/197)
1.64
(1/61)
0.0
(0/16)
10.0
(1/10)
0.462
Early abortion rate 11.67a
(106/908)
8.31
(53/638)
8.72
(13/149)
15.79
(18/114)
21.43
(12/56)
0.037 20.0
(16/80)
17.26
(34/197)
13.11
(8/61)
18.75
(3/16)
30.0
(3/10)
0.758
Abortion rate 13.33
(121/908)
11.44
(73/638)
9.40
(14/149)
19.30
(22/114)
21.43
(12/56)
0.067 21.25
(17/80)
18.78
(37/197)
14.75
(9/61)
25.0
(4/16)
30.0
(3/10)
0.715
Ectopic pregnancy rate 0.88
(8/908)
1.25
(8/638)
1.34
(2/149)
0.0
(0/114)
0.0
(0/56)
0.597 2.50
(2/80)
0.0
(0/197)
0.0
(0/61)
0.0
(0/16)
10.0
(1/10)
0.076
  1. #comparison among groups A–D. P < .05 was considered statistically significant
  2. aP < .05 compared to group B
  3. bP < .05 compared to group C
  4. cP < .05 compared to group D
  5. dP < .05 between groups D and E