Skip to main content

Table 3 Maternal characteristics for Normal vs Low PlGF values in the Extension data, (n (%) or median (interquartile range))

From: Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

Characteristics Low PlGF
(<  100 pg/ml),
n (%) or median (IQR),
(n = 485)
Normal PlGF
(≥100 pg/ml),
n (%) or median (IQR),
(n = 56)
DEMOGRAPHICS & PREGNANCY CHARATERISTICS
Maternal age at EDD (year) 30 [24, 34] 29 [26, 34]
Parity ≥ 1 192 (39.6%) 27 (48.2%)
Gestational age at eligibility (week) 32.6 [29.6, 35.7] 35.2 [33.4, 36.8]
Gestational age at eligibility < 35 weeks, N 329 (67.8%) 26 (46.4%)
Multiple pregnancy 40 (8.2%) 3 (5.4%)
Smoking in this pregnancy 101 (20.8%) 17 (30.4%)
CLINICAL MEASURES
Systolic BP (mm Hg) 144 [135, 155] 136 [126, 150]
Diastolic BP (mm Hg) 86 [78, 94] 80 [74, 91]
Uric acid 375 [315, 435] 297 [256, 351]
Lowest platelet count (× 109 per L) 199 [154, 243] 226 [160, 251]
Highest AST/ALT (U/L) 24 [19, 37] 18 [16, 24]
Creatinine 62 [53, 71] 53 [44, 62]
INTERVENTIONS DURING ADMISSION
Corticosteroids, GA onset < 35 127/329 (38.6%) 7/26 (26.9%)
Antihypertensive therapy 348 (71.8%) 36 (64.3%)
MgSO4 376 (77.5%) 34 (60.7%)
PREGNANCY OUTCOMES
Admission-To-Delivery Interval (Days) 2 [1, 4] 2 [1, 7]
Gestational age at delivery (week) 33.3 [30·1, 36.3] 36.1 [34.7, 37.3]
Stillbirth 10 (2.1%) 0
Neonatal death 12 (2.5%) 0
MATERNAL OUTCOME (N women)
Within 48 h 41 (8.5%) 3 (5.4%)
Within 7 days 49 (10.1%) 3 (5.4%)
At anytime 53 (10.9%) 4 (7.1%)
PlGF measurement-To-adverse maternal outcome Interval (at any time, Days) 3 [2, 6]
Mean = 4
3 [1, 5]
Mean = 2
  1. Abbreviations: AST (aspartate aminotransferase), BP (blood pressure), EDD (estimated date of delivery), MgSO4 (magnesium sulphate)