Table 3 Maternal characteristics for Normal vs Low PlGF values in the Extension data, (n (%) or median (interquartile range))
Characteristics | Low PlGF (<  100 pg/ml), n (%) or median (IQR), (n = 485) | Normal PlGF (≥100 pg/ml), n (%) or median (IQR), (n = 56) |
|---|---|---|
DEMOGRAPHICS & PREGNANCY CHARATERISTICS | ||
 Maternal age at EDD (year) | 30 [24, 34] | 29 [26, 34] |
 Parity ≥ 1 | 192 (39.6%) | 27 (48.2%) |
 Gestational age at eligibility (week) | 32.6 [29.6, 35.7] | 35.2 [33.4, 36.8] |
 Gestational age at eligibility < 35 weeks, N | 329 (67.8%) | 26 (46.4%) |
 Multiple pregnancy | 40 (8.2%) | 3 (5.4%) |
 Smoking in this pregnancy | 101 (20.8%) | 17 (30.4%) |
CLINICAL MEASURES | ||
 Systolic BP (mm Hg) | 144 [135, 155] | 136 [126, 150] |
 Diastolic BP (mm Hg) | 86 [78, 94] | 80 [74, 91] |
 Uric acid | 375 [315, 435] | 297 [256, 351] |
 Lowest platelet count (× 109 per L) | 199 [154, 243] | 226 [160, 251] |
 Highest AST/ALT (U/L) | 24 [19, 37] | 18 [16, 24] |
 Creatinine | 62 [53, 71] | 53 [44, 62] |
INTERVENTIONS DURING ADMISSION | ||
 Corticosteroids, GA onset < 35 | 127/329 (38.6%) | 7/26 (26.9%) |
 Antihypertensive therapy | 348 (71.8%) | 36 (64.3%) |
 MgSO4 | 376 (77.5%) | 34 (60.7%) |
PREGNANCY OUTCOMES | ||
 Admission-To-Delivery Interval (Days) | 2 [1, 4] | 2 [1, 7] |
 Gestational age at delivery (week) | 33.3 [30·1, 36.3] | 36.1 [34.7, 37.3] |
 Stillbirth | 10 (2.1%) | 0 |
 Neonatal death | 12 (2.5%) | 0 |
MATERNAL OUTCOME (N women) | ||
 Within 48 h | 41 (8.5%) | 3 (5.4%) |
 Within 7 days | 49 (10.1%) | 3 (5.4%) |
 At anytime | 53 (10.9%) | 4 (7.1%) |
PlGF measurement-To-adverse maternal outcome Interval (at any time, Days) | 3 [2, 6] Mean = 4 | 3 [1, 5] Mean = 2 |