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Table 4 Factors associated with Preterm Birth and Low Birth Weight (n = 760)

From: Maternal demographic and antenatal factors, low birth weight and preterm birth: findings from the mother and child in the environment (MACE) birth cohort, Durban, South Africa

 

Crude Odds Ratio

p-value

Adjusted Odds Ratio (95% CI)

p-value

Preterm Birth

 Maternal age

  Prime fertility age (20–30 years)

1

 

1

 

  Teenager (15–19 years)

1.2

0.5

1.2 (0.6–2.3)

0.6

  Middle aged (>  30 years)

1.7

0.02

1.8 (1.1–2.9)

0.01

 Maternal BMI at trimester 1

  Normal BMI (18.5–24.9 kg/m2)

1

 

1

 

  Low BMI (<  18.5 kg/m2)

1.4

0.4

0.9 (0.4–2.4)

0.9

  High BMI (25–29.9 kg/m2)

0.6

0.03

0.5 (0.3–0.9)

0.02

  Obese (>  30 kg/m2)

0.6

0.03

0.5 (0.3–0.9)

0.01

Past history of tuberculosis

3.5

0.02

2.0 (0.6–6.6)

0.3

Past history of sexually transmitted infections

2.6

0.2

2.7 (0.6–12.2)

0.2

Syphilis

0.3

0.02

0.4 (0.1–0.9)

0.04

Hypertension

 Normotensive

  Chronic

0.7

0.8

0.8 (0.09–6.7)

0.8

  PIH

1.1

0.9

0.5 (0.06–4.2)

0.5

HIV positive

1.4

0.1

1.4 (1.0–2.2)

0.1

Current Smoker

3.22

0.001

2.7 (1.3–5.8)

0.01

 Delivery Type

  Normal delivery

1

 

1

 

  Caesarian section

1.54

0.03

1.7 (1.1–2.7)

0.01

Low Birth Weight

 Weight gain

  Normal

1

 

1

 

  High (>  6.3 kg)a

0.74

0.2

0.6 (0.4–1.03)

0.07

 Maternal age

  Prime fertility age (20–30 years)

1

 

1

 

  Teenager (15–19 years)

1.7

0.1

1.6 (0.9–3.1)

0.1

  Middle aged (> 30 years)

1.4

0.1

1.7 (1.0–2.9)

0.07

 Maternal BMI at trimester 1

  Normal (18.5–24.9)

1

 

1

 

  Low BMI (< 18.5 kg/m2)

1.7

0.2

1.3 (0.5–3.3)

0.5

  High BMI (25–29.9 kg/m2)

0.5

0.01

0.5 (0.3–0.8)

0.01

  Obese (>  30 kg/m2)

0.5

0.02

0.4 (0.2–0.7)

0.002

Past history of sexually transmitted infections

3.3

0.09

4.2 (1.0–18.3)

0.06

Syphilis

0.7

0.4

1.0 (0.6–1.7)

0.9

 Hypertension

  Normotensive

1

 

1

 

  Chronic

Not available

 

Not available

 

  PIH

1.4

0.6

1.2 (0.1–10.6)

0.9

HIV Positive

1.2

0.5

1.2 (0.8–2.03)

0.4

 Smoking

  Non-smoker

1

 

1

 

  Current-smoker

2.4

0.03

1.9 (0.8–4.3)

0.1

 Delivery Type

  Normal delivery

1

 

1

 

  Caesarian section

1.4

0.1

1.7 (1.1–2.7)

0.03

  1. aMean weight gain across the first and third trimester for mothers during this pregnancy
  2. - LBW (Yes = 1, No = 0), with “YES” when LBW < 2500 g
  3. CI Confidence interval; BMI Body mass index; Ref Reference; PIH Pregnancy induced hypertension; HIV Human immunodeficiency virus; NVD Normal vaginal delivery