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Table 2 Summary of fetal and maternal outcomes

From: Ex-Utero Intrapartum Treatment (EXIT): indications and outcome in fetal cervical and oropharyngeal masses

Case

Single /twin pregnancy

Maternal age (years)

GA at diagnosis (weeks)

Ultrasonographic findings

Prenatal MRI

Preoperative interventions

GA at birth (weeks)

Duration of EXIT (min)

Neonatal procedure

Fetal weight (g)

Airway obstruction

Postnatal therapy

Pathological diagnosis

1

Single pregnancy

28

30

Cystic left-cervical mass size of 65 × 50 × 50 mm, extending from parapharyngeal space at cavum level to supraclavicular space

Yes

No

38

6

Endotracheal intubation

3407

++

Surgical resection

Teratoma

2

Single pregnancy

37

34

Pediculated solid oropharyngeal mass with a maximum diameter of 40 mm

Yes

No

37

3

Endotracheal intubation by bronchoscopy

3100

+

Surgical resection

Epulis

3

Single pregnancy

30

20

Cystic right-cervical mass with a maximum diameter of 63 mm. The tumor crosses the midline and enters the upper mediastinum, compressing and displacing pharynx and larynx. Severe polyhydramnios

Yes

No

36

22

Endotracheal intubation

2900

++

Surgical resection and sclerosing substance injection

Lymphangiomatosis

4

Single pregnancy

28

36

Large macrocystic cervical mass with a maximum diameter of 80 mm. The tumor enters the upper mediastinum, with a tracheal and esophageal displacement

Yes

No

37

7

Endotracheal intubation

3170

++

Treatment with sirolimus

Not performed (mass not excised)

5

Single pregnancy

41

34

Cystic bilateral -cervical mass size of 60 × 56 × 33 mm, with deep facial infiltration and polyhydramnios

Yes

No

36

9

Endotracheal intubation

2889

+

Treatment with sirolimus

Not performed (mass not excised)