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Table 2 Summary of fetal and maternal outcomes

From: Ex-Utero Intrapartum Treatment (EXIT): indications and outcome in fetal cervical and oropharyngeal masses

Case Single /twin pregnancy Maternal age (years) GA at diagnosis (weeks) Ultrasonographic findings Prenatal MRI Preoperative interventions GA at birth (weeks) Duration of EXIT (min) Neonatal procedure Fetal weight (g) Airway obstruction Postnatal therapy Pathological diagnosis
1 Single pregnancy 28 30 Cystic left-cervical mass size of 65 × 50 × 50 mm, extending from parapharyngeal space at cavum level to supraclavicular space Yes No 38 6 Endotracheal intubation 3407 ++ Surgical resection Teratoma
2 Single pregnancy 37 34 Pediculated solid oropharyngeal mass with a maximum diameter of 40 mm Yes No 37 3 Endotracheal intubation by bronchoscopy 3100 + Surgical resection Epulis
3 Single pregnancy 30 20 Cystic right-cervical mass with a maximum diameter of 63 mm. The tumor crosses the midline and enters the upper mediastinum, compressing and displacing pharynx and larynx. Severe polyhydramnios Yes No 36 22 Endotracheal intubation 2900 ++ Surgical resection and sclerosing substance injection Lymphangiomatosis
4 Single pregnancy 28 36 Large macrocystic cervical mass with a maximum diameter of 80 mm. The tumor enters the upper mediastinum, with a tracheal and esophageal displacement Yes No 37 7 Endotracheal intubation 3170 ++ Treatment with sirolimus Not performed (mass not excised)
5 Single pregnancy 41 34 Cystic bilateral -cervical mass size of 60 × 56 × 33 mm, with deep facial infiltration and polyhydramnios Yes No 36 9 Endotracheal intubation 2889 + Treatment with sirolimus Not performed (mass not excised)