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Table 1 Sensitivity, Specificity, and AUC of each biomarker under Bayesian latent class model assuming without a gold standard

From: Diagnostic accuracy of maternal serum multiple marker screening for early detection of gestational diabetes mellitus in the absence of a gold standard test

BiomarkerParametersMeanMedianSDMC error95% CrIa
uE3
 Sensitivity0.670.660.150.020.58–0.72
Specificity0.860.880.0020.00070.81–0.88
AUC0.650.650.120.010.56–0.69
β-hCG
 Sensitivity0.780.770.200.030.70–0.84
Specificity0.820.820.0030.00070.79–0.85
AUC0.620.620.180.040.54–0.68
AFP
 Sensitivity0.710.700.060.0020.66–0.78
Specificity0.920.930.060.0020.89–0.98
AUC0.580.580.070.0020.51–0.62
  1. uE3 unconjugated estriol, β-hCG beta-human chorionic gonadotropin, AFP alfa-Fetoprotein, SD standard deviation, MC monte carlo, CrI credible interval, AUC area under receiver operating characteristic curve