Table 1 Baseline characteristics of mothers with and without AFLP(n = 275)
From: Pregnancy outcomes of patients with acute fatty liver of pregnancy: a case control study
AFLP Group (n = 55) | Control Group (n = 220) | t/χ2/Z, P | |
|---|---|---|---|
Age (mean ± SD, years) | 28.53 ± 4.71 | 31.31 ± 4.20 | t = 4.3, P = 2.8*10−6 |
Gravidity, n (%) | |||
1 | 28 (50.9) | 89 (40.9) | Z = 1.7, P = 0.087 |
2 | 16 (29.1) | 62 (28.2) | |
> 2 | 11 (20) | 69 (30.1) | |
Multiparae, n (%) | 22 (40) | 87 (39.5) | χ2 = 0.004, P = 0.951 |
Complications before the AFLP onset, n (%) | |||
Hypothyroidism during pregnancy | 2 (3.6) | 9 (4.1) | *χ2 = 0, P = 1 |
PIH | 12 (21.8) | 6 (2.7) | χ2 = 26.2, P = 3.1*10−7 |
GDM | 3 (5.5) | 29 (13.2) | χ2 = 2.5, P = 0.11 |
Placenta previa | 2 (3.6) | 4 (1.8) | *χ2 = 0.096, P = 0.76 |
Twins | 6 (10.9) | 3 (1.4) | *χ2 = 9.8, P = 0.002 |
FGR | 4 (7.3) | 3 (1.4) | *χ2 = 4.0, P = 0.044 |
Fetal gender (male) | 53 (96.4) | 121 (55) | *χ2 = 32.3, P = 1.3*10− 8 |
Lab on first visit (mean ± SD) | |||
Platelet (*109/L) | 130.53 ± 70.16 | 205.35 ± 56.03 | t = 8.4, P = 4.4*10−15 |
Hemoglobin(g/L) | 104.27 ± 23.44 | 120.13 ± 12.40 | t = 4.8, P = 9.0*10−6 |
ALT (IU/L) | 219.18 ± 240.11 | 14.35 ± 27.65 | t = 6.3, P = 5.2*10−8 |
Serum Glucose (umol/L) | 4.00 ± 1.57 | 4.67 ± 2.82 | t = 1.4, P = 1.2 |
Hypoglycemia (%) | 34 (61.8) | 46 (20.9) | *χ2 = 35.7, P = 2.3*10−9 |
Hyperglycemia(%) | 4 (7.3) | 8 (3.6) | *χ2 = 0.66, P = 0.42 |
TBA (umol/L) | 89.45 ± 56.89 | 3.26 ± 4.11 | t = 9.7, P = 4.6*10−12 |
Albumin(g/L) | 25.54 ± 4.67 | 33.26 ± 3.99 | t = 12.1, P = 8.9*10−27 |
Total Bilirubin (umol/L) | 160.83 ± 112.54 | 9.33 ± 5.44 | t = 10.0, P = 7.2*10−14 |
Prothrombin activity(%) | 40.44 ± 23.37 | 119.05 ± 13.23 | t = 23.8, P = 7.3*10−33 |
Creatinine (umol/L) | 162.91 ± 89.84 | 46.83 ± 11.62 | t = 9.6, P = 3.0*10−13 |