Association between hypertensive pregnancy disorders and future risk of stroke in Taiwan: a Nationwide population-based retrospective case-control study

Huang, Chun-Chung; Huang, Chien-Chu; Lin, Shao-Yi; Chang, Cherry Yin-Yi; Lin, Wu-Chou; Chung, Chi-Hsiang; Lin, Fu-Huang; Tsao, Chang-Huei; Lo, Chun-Min; Chien, Wu-Chien

doi:10.1186/s12884-020-02898-9

Table 1 Characteristics of the study population in regard to the endpoint

From: Association between hypertensive pregnancy disorders and future risk of stroke in Taiwan: a Nationwide population-based retrospective case-control study

Hypertensive pregnancy disorders	Total		With		Without		P
Variables	n	%	n	%	n	%	P
Total	167,480		41,870	25.00	125,610	75.00
Stroke subgroup							< 0.001
Without	166,584	99.47	41,672	99.53	124,912	99.44
Acute, but ill-defined, cerebrovascular disease	201	0.12	80	0.19	121	0.10
Other and ill-defined cerebrovascular disease	695	0.41	118	0.28	577	0.46
Age (years)	36.41 ± 7.07		35.49 ± 6.44		36.71 ± 7.28		< 0.001
Age group (years)							< 0.001
12–19	1645	0.98	418	1.00	1227	0.98
20–29	48,363	28.88	13,191	31.50	35,172	28.00
30–39	90,913	54.28	22,212	53.05	68,701	54.69
40–49	24,790	14.80	5666	13.53	19,124	15.22
≧50	1769	1.06	383	0.91	1386	1.10
Insurance premium (USD)							< 0.001
< 7200	159,022	94.95	39,979	95.48	119,043	94.77
7200-13,999	7222	4.31	1511	3.61	5711	4.55
≥ 14,000	1236	0.74	380	0.91	856	0.68
DM	2950	1.76	1165	2.78	1785	1.42	< 0.001
HTN	3096	1.85	1379	3.29	1717	1.37	< 0.001
Hyperlipidemia	893	0.53	312	0.75	581	0.46	0.224
Obesity	129	0.08	59	0.14	70	0.06	0.001
Heart disease	2708	1.62	684	1.63	2024	1.61	0.892
CKD	1394	0.83	377	0.90	1017	0.81	0.794
Season							< 0.001
Spring	36,206	21.62	9454	22.58	26,752	21.30
Summer	47,389	28.30	10,265	24.52	37,124	29.55
Autumn	41,478	24.77	11,104	26.52	30,374	24.18
Winter	42,407	25.32	11,047	26.38	31,360	24.97
Location							< 0.001
Northern Taiwan	67,388	40.24	17,254	41.21	50,134	39.91
Middle Taiwan	43,559	26.01	10,134	24.20	33,425	26.61
Southern Taiwan	40,128	23.96	10,004	23.89	30,124	23.98
Eastern Taiwan	15,413	9.20	4101	9.79	11,312	9.01
Surrounding islands	992	0.59	377	0.90	615	0.49
Urbanization level							< 0.001
1 (The highest)	63,431	37.87	15,297	36.53	48,134	38.32
2	75,770	45.24	19,784	47.25	55,986	44.57
3	10,955	6.54	2111	5.04	8844	7.04
4 (The lowest)	17,324	10.34	4678	11.17	12,646	10.07
Level of care							< 0.001
Hospital center	47,476	28.35	13,701	32.72	33,775	26.89
Regional hospital	56,621	33.81	15,765	37.65	40,856	32.53
Local hospital	63,383	37.85	12,404	29.63	50,979	40.59

P: Chi-square/Fisher exact test for categorical variables and t-test for continuous variables

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ISSN: 1471-2393

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