Serum homocysteine and folate concentrations in early pregnancy and subsequent events of adverse pregnancy outcome: the Sichuan Homocysteine study

Table 3 Univariate logistic regression analysis of the association between APO events with each of the early pregnancy variables in 1163 pregnant women

Variables	II vs I quartile				III vs I quartile				IV vs I quartile
Variables	Odds ratio	95% CI	Wald	P value	Odds ratio	95% CI	Wald	P value	Odds ratio	95% CI	Wald	P value
Hcy	1.03	0.74–1.44	0.03	0.863	1.28	0.92–1.78	2.08	0.149	6.16	4.27–8.89	94.79	< 0.001
Folate	0.65	0.47–0.91	6.36	0.012	0.40	0.28–0.55	29.48	< 0.001	0.30	0.22–0.42	47.73	< 0.001
VB12	0.71	0.51–0.98	4.29	0.038	0.70	0.50–0.97	4.63	0.031	0.63	0.45–0.87	7.69	0.006
hs-CRP	0.75	0.54–1.04	3.05	0.081	1.10	0.79–1.52	0.34	0.562	1.14	0.82–1.58	0.63	0.430
IL-6	1.23	0.89–1.70	1.55	0.213	1.32	0.95–1.83	2.75	0.097	1.19	0.86–1.65	1.08	0.300
TC	1.05	0.76–1.46	0.11	0.739	0.97	0.70–1.35	0.03	0.868	1.60	1.15–2.21	7.70	0.006
TG	1.06	0.76–1.46	0.11	0.74	1.18	0.85–1.63	0.99	0.319	1.31	0.94–1.81	2.61	0.106
LDL-C	0.77	0.55–1.01	2.51	0.114	0.97	0.70–1.35	0.028	0.868	1.33	0.96–1.84	2.90	0.089
HDL-C	0.67	0.48–0.92	5.97	0.015	0.65	0.47–0.90	6.58	0.010	0.64	0.46–0.89	7.01	0.008
FPG	1.10	0.79–1.53	0.34	0.560	1.28	0.92–1.77	2.22	0.135	1.29	0.93–1.79	2.35	0.125
UA	1.13	0.82–1.57	0.56	0.455	0.91	0.66–1.26	0.34	0.560	1.27	0.92–1.76	2.11	0.147
SBP	1.34	0.97–1.86	3.08	0.079	1.36	0.98–1.89	3.37	0.066	2.20	1.58–3.06	21.69	< 0.001
DBP	1.01	0.73–1.41	0.01	0.933	1.27	0.91–1.76	2.00	0.158	1.88	1.35–2.62	14.14	< 0.001
BMI	1.12	0.81–1.56	0.45	0.501	1.65	1.19–2.29	8.91	0.003	2.05	1.47–2.85	18.07	< 0.001
Age	0.89	0.64–1.24	0.45	0.503	1.18	0.85–1.64	0.99	0.319	1.73	1.25–2.40	10.69	0.001

ISSN: 1471-2393