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Table 3 Haplotype analysis of TaqI, ApaI, and FokI variants of the VDR gene in mothers and their preterm and full-term newborns

From: Association between vitamin D plasma concentrations and VDR gene variants and the risk of premature birth

Population

Haplotypes

Preterm

Full-term

P*

TaqI (A > G)

ApaI (C > A)

FokI

(A > G)

Frequency

(%)

Frequency

(%)

Mothers

 

A

A

G

33.5

20.4

0.022

 

G

C

G

5.8

22.5

0.001

 

A

C

A

14.5

14.8

0.947

 

A

C

G

15.8

12.0

0.395

 

G

A

G

12.5

7.7

0.213

 

G

C

A

2.7

1.1

0.025

 

G

A

A

9.1

6.6

0.477

 

A

A

A

6.2

5.0

0.687

Newborns

 

A

A

G

34.6

26.7

0.188

 

A

C

G

17.3

20.1

0.595

 

A

C

A

10.4

12.2

0.670

 

G

C

A

4.0

13.5

0.021

 

G

A

G

18.5

5.6

0.001

 

G

C

G

3.3

9.1

0.099

 

A

A

A

2.7

8.4

0.085

 

G

A

A

9.2

4.4

0.131

  1. *Software Haploview version 4.1. P < 0.05