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Table 6 Univariate and Multivariate analysis of Mode of delivery in TOLAC matched by PSM

From: Effect of epidural analgesia in trial of labor after cesarean on maternal and neonatal outcomes in China: a multicenter, prospective cohort study

Variable

Univariate(n = 236)

Multivariate(n = 236)

P

OR (95%CI)

P

OR (95%CI)

Epidural analgesia

< 0.001

4.361(2.202–9.198)

< 0.001

4.480(2.025–10.660)

Hospital name

 MCH

 

1(reference)

  

 BA

0.608

1.265(0.539–3.331)

  

 LG

0.984

0.000(NA-13382569087647956.000)

  

General information

 Age (y)

0.892

1.006(0.923–1.095)

  

 Gestational age (day)

0.443

0.987(0.952–1.014)

  

 BMI (kg/m2)

0.211

0.940(0.851–1.038)

  

 Maternal education > 12 y

0.078

0.494(0.213–1.042)

  

 Husband education > 12 y

0.283

0.648(0.278–1.380)

  

 Housewives

0.523

1.515(0.480–6.705)

  

History of pregnancy and childbirth

 History of previous vaginal delivery

0.203

2.641(0.728–16.976)

  

Gravidity time (times)

 2

 

1(reference)

  

 3

0.462

0.776(0.389–1.511)

  

 > 3

0.237

2.027(0.682–7.493)

  

Time from last cesarean section (year)

 ≤ 3

 

1(reference)

  

 3–5

0.188

2.723(0.532–11.823)

  

 > 5

0.496

1.691(0.325–7.484)

  

Progress of Labor in previous caesarean section (cervical dilation: cm)

 0

 

1(reference)

 

1(reference)

 < 3

0.013

2.601(1.260–5.731)

0.168

1.811(0.794–4.361)

 ≥ 3

0.462

1.451(0.565–4.235)

0.892

0.927(0.320–2.974)

 10

0.988

17,640,531.947(0.000-NA)

0.988

9,284,640.473(0.000-NA)

 Cervical score at admission (score)

0.004

1.269(1.082–1.494)

0.003

1.360(1.113–1.673)

 Cervical dilation at admission (cm) ≥3

0.068

2.742(1.028–9.522)

  

 Effacement

0.927

1.034(0.493–2.069)

  

 The onset of labor: Spontaneous

< 0.001

20.754(6.329–93.768)

< 0.001

10.188(2.875–48.418)

 Oxytocin during labor

0.487

0.719(0.295–1.939)

  

 HGB (g/L:115–150)

0.592

0.994(0.973–1.017)

  

 PLT (125–350)

0.62

0.999(0.993–1.004)

  

Neonatal

 Weight(g) ≥3500

0.304

0.682(0.334–1.452)

  
  1. OR Odds ratio, CI Confidence interval, PSM Propensity score matching
  2. Data had been matched by using propensity score matching with 1:1 nearest neighbor matching. Multivariable logistic regression after PSM included entered factors variable as p < 0.05 (Epidural analgesia, Progress of Labor in previous caesarean section, Cervical score at admission, the onset of labor: Spontaneous) and using stepwise regression by AIC criteria. Hosmer-Lemeshow goodness of fit (GOF) test: Chi-squared = 13.627, df = 8, P value = 0.092 McFadden’s pseudo-R squared =0.232 Cox & Snell pseudo-R squared = 0.215 Nagelkerke pseudo-R squared =0.332. All VIFs < 2