Table 1 Clinical features of overall hypothyroid pregnancies at Aga Khan University
Clinical characteristics | Frequency (%) N = 708 |
|---|---|
Age (years) | |
 Age 18–25 | 87 (12.3) |
 Age 26–33 | 403 (56.9) |
 Age 34–40 | 200 (28.2) |
 Age 41–47 | 18 (2.5) |
Parity | |
 Nulliparous | 216 (31.4) |
 Primiparous | 221 (32.2) |
 Biparous | 140 (20.4) |
 Multiparous | 110 (16.0) |
 Missing | 21 (3.0) |
Body Mass Index (Kg/m2) | |
 Underweight (< 18.5) | 19 (2.7) |
 Normal (18.5–24.9) | 177 (25.0) |
 Overweight (25–29.9) | 221 (31.2) |
 Obesity class I (30–34.9) | 150 (21.2) |
 Obesity class II and above (> = 35) | 47 (6.6) |
 Unknown | 94 (13.3) |
Gestational age at antenatal visit (weeks of pregnancy) | 11 (7–19) |
Mode of labor (for live births only; N = 638) | |
 Spontaneous | 145 (22.7) |
 Induced | 157 (24.6) |
 Augmented | 76 (11.9) |
 Not applicable (because of caesarian section) | 260 (40.8) |
Mode of delivery (for live births only; N = 638) | |
 Em-LSCS | 149 (23.4) |
 LSCS | 223 (35.0) |
 Instrumental | 23 (3.6) |
 SVD | 87 (13.6) |
 SVD with Episiotomy | 156 (24.5) |
Gestational age at delivery (weeks) | 38 (37–39) |
Hypothyroidism diagnosed during pregnancy | |
 Uncategorized | 14 (2.0) |
 Overt hypothyroidism | 13 (1.8) |
 Subclinical hypothyroidism | 43 (6.1) |
Hypothyroidism diagnosed prior to pregnancy | |
 Uncategorized | 308 (43.5) |
 Overt hypothyroidism | 86 (12.6) |
 Subclinical hypothyroidism | 217 (30.6) |
Neither preconceptional nor Gestational Hypothyroidism | 27 (3.8) |
Etiology of Hypothyroidism | |
 Hashimoto’s | 183 (25.8) |
 Post Radioactive Iodine ablation | 8 (1.1) |
 Post-surgical | 6 (0.8) |
 Postpartum thyroiditis | 4 (0.6) |
 Secondary Hypothyroidism | 1 (0.1) |
 After medical treatment for Grave’s Disease | 2 (0.3) |
 Congenital | 1 (0.1) |
 Nodular Goiter | 2 (0.3) |
 Subacute thyroiditis | 1 (0.1) |
 Unknown | 500 (70.6) |
Thyroid antibodies | |
 Positive | 158 (22.3) |
 Negative | 57 (8.1) |
 Not checked | 493 (69.6) |
Comorbidities (positive cases only) | |
 Diabetes mellitus | 55 (7.8) |
 Gestational diabetes | 150 (21.2) |
 Hypertension | |
  Pregnancy Induced Hypertension | 75 (10.6) |
  Chronic Hypertension | 34 (4.8) |
 Smoking | 1 (0.1) |