Pregnancy following kidney transplantation - impact on mother and graft function and focus on childrens’ longitudinal development

Table 3 Pregnancy outcome until 2 years after delivery

Patients	n = 28
Number of pregnancies	32
Median gestational age (weeks), IQR	34.7(31.9, 36.3)
Delivery
Vaginal birth	8(25%)
Caesarean section without labor*	22(68.8%)
Caesarean section with labor	2(6.2%)
Preeclampsia	5(15.6%)
Gestational diabetes	2(6.2%)
Indication for caesarean section
Maternal	16(66.7%)
Fetal	5(20.8%)
Combined (maternal and fetal)	3(12.5%)
Renal outcome
Pre-pregnancy GFR _(CKD-EPI) (ml/min/1,73m²), median (IQR)	57(52, 78)
GFR _(CKD-EPI) at delivery	49(37, 59)^a
GFR _(CKD-EPI) 12 months after delivery	50(39, 69)^b
GFR _(CKD-EPI) 24 months after delivery	47(41, 80)
Graft failure within 24 months after delivery	2(6.2%)
Proteinuria
Proteinuria at delivery, mg/g creatinine, median (range)	335(100–4000)

All 32 pregnancies resulting in life births are evaluated. The indication for caesarean section is evaluated in 24 pregnancies and is subdivided in three groups (maternal/ fetal/ combined maternal and fetal). GFR, glomerular filtration rate. IQR, interquartile range
*two emergency caesarean section due to aortic dissection due to severe hypertensive disorder and major placental abruption
eGFR _(CKD-EPI), estimated glomerular filtration rate. ^aP 0.005 and ^bP 0.001 versus GFR _(CKD-EPI) at pre-pregnancy

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