Early prediction of preeclampsia and small-for-gestational-age via multi-marker model in Chinese pregnancies: a prospective screening study

Table 3 AUC curves of different PE risks with the best fit cut-off values

	Type of risk	AUC, 95%CI	cut-off value	DR%, 95CI	FPR%, 95CI
Early PE	Prior Risk	0.509 (0.491–0.526)	1:54	25 (3.2–65.1)	0.31 (0.1–0.6)
Early PE	Posterior Risk	0.901 (0.890–0.911)*	1:45	87.5 (47.3–99.7)	3.94 (3.3–4.7)
Late PE	Prior Risk	0.762 (0.747–0.776)	1:102	48.57 (31.4–66.0)	9.05 (8.1–10.1)
Late PE	Posterior Risk	0.828 (0.814–0.840)	1:151	80.00 (63.1–91.6)	25.81 (24.3–27.4)

AUC = Area under the receiver operating characteristics curve, DR = Detection rate, FPR = False positive rate, 95% CI = 95% Confidence interval. Cut-off values of different risks are at the highest average of sensitivity and specificity, and DRs and FPRs are shown at the best fit cut-off value of each type of risk. Pairwise comparison of ROC curves between prior risk and posterior risk in early PE and late PE individually, and significance level: * P < 0.05

ISSN: 1471-2393